Results 151 to 160 of about 18,599 (272)
Salvage enzymes in nucleotide biosynthesis [PDF]
Balanced pools of deoxyribonucleoside triphosphates (dNTPs), the building blocks of DNA, and ribonucleoside triphosphates (NTPs), the precursors of RNA, are crucial for a controlled cell proliferation.
Kosinska, Urszula
core
Poly (adenosine 5′-diphosphate-ribose) polymerase inhibitors (PARPi) are increasingly important in the treatment of ovarian cancer. However, more than 40% of BRCA1/2-deficient patients do not respond to PARPi, and BRCA wild-type cases do not show obvious
Nayiyuan Wu +13 more
doaj +1 more source
Poly(adenosine diphosphate-ribose) synthesis in transformed mouse epidermal cells in culture.
Kouichi Ikai +2 more
openalex +2 more sources
Valsartan improves resting skin blood flow in type 2 diabetic patients and reduces poly(adenosine diphosphate-ribose) polymerase activation [PDF]
Gautam Shrikhande +8 more
openalex +1 more source
Methylation status of Dnmt1 promoter depends on poly(ADP-ribosy)lation [PDF]
Research is focused on CpG islands and on the mechanism that poly(ADP-ribosyl)ation uses to defend the unmethylated state of these important DNA sequences which are located in the promoter regions of the housekeeping genes having a role of transcription ...
Zampieri, Michele
core
Studies on Poly Adenosine Diphosphate-Ribose
Teruo Shima +4 more
openaire +1 more source
Poly(ADP-Ribosyl)ation affects stabilization of CHE-1 protein in response to DNA damage [PDF]
Post-translation modifications play a crucial role in coordinating the cellular response to DNA damage. Double strand DNA breaks (DSBs) trigger the activation of ATM and Chk2 kinases, which represent the primary transducers in the signalling cascade ...
BACALINI, MARIA GIULIA
core
Metabolism and Congenital Malformations — NAD’s Effects on Development [PDF]
Vander Heiden, Matthew G.
core +1 more source

