BRCA1 CpG Island Hypermethylation Predicts Sensitivity to Poly(Adenosine Diphosphate)- Ribose Polymerase Inhibitors [PDF]
, 2010 Jürgen Veeck +7 more
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Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites [PDF]
, 2017 Poly(ADP-ribose) polymerase 1 (PARP1) synthesizes poly(ADP-ribose) (PAR) using nicotinamide adenine dinucleotide (NAD) as a substrate. Despite intensive research on the cellular functions of PARP1, the molecular mechanism of PAR formation has not been ...
Altmeyer, Matthias +4 more
core
Properties of Purified Calf Thymus Poly(Adenosine Diphosphate Ribose) Polymerase. Comparison of the DNA-Independent and the DNA-Dependent Enzyme [PDF]
, 1979 Claude Niedergang +2 more
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Inhibitors targeting CDK4/6, PARP and PI3K in breast cancer: a review
Therapeutic Advances in Medical Oncology, 2018 Breast cancer is the global leading cause of cancer-related death in women and it represents a major health burden worldwide. One of the promising breast cancer therapeutic avenues is through small molecule inhibitors (SMIs) which have undergone rapid ...
Siti Muhamad Nur Husna +4 more
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Tumor treating fields combined with a poly (adenosine diphosphate-ribose) polymerase inhibitor during radiotherapy for rapidly progressing IDH-wildtype diffuse astrocytoma: a case report. [PDF]
J Int Med Res, 2021 Wang Z, Ren Y, Du F, Sun Y, Jiang W.
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Antibodies to the five histones and poly(adenosine diphosphate-ribose) in drug induced lupus: implications for pathogenesis. [PDF]
, 1987 R N Hobbs +2 more
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Oncology in Clinical PracticeMetastatic pancreatic cancer (mPC) is usually diagnosed at an advanced stage, and systemic therapy is still the main treatment option. Pathological germline mutations in the BRCA1 or BRCA2 genes are present in aroun 4–7% of cases of pancreatic cancer (PC)
Agata I. Adamczuk-Nurzyńska +2 more
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Patient cost sharing during poly(adenosine diphosphate-ribose) polymerase inhibitor treatment in ovarian cancer. [PDF]
Am J Obstet Gynecol, 2021 Harrison RF +6 more
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Gonadotropin-Releasing Hormone Antagonist Cetrorelix Down-Regulates Proliferating Cell Nuclear Antigen and Epidermal Growth Factor Expression and Up-Regulates Apoptosis in Association with Enhanced Poly(Adenosine 5′-Diphosphate-Ribose) Polymerase Expression in Cultured Human Leiomyoma Cells [PDF]
, 2005 Wei Chen +5 more
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Studies on Poly (Adenosine Diphosphate Ribose)
Journal of Biological Chemistry, 1970 Hirotaka Matsubara +5 more
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