Results 21 to 30 of about 15,767 (251)

Human autoantibodies to poly(adenosine diphosphate-ribose) polymerase. [PDF]

Journal of Clinical Investigation, 1987
The chromatin-bound enzyme poly(ADP-ribose) polymerase (ADPRP) is strongly stimulated by DNA with single- or double-stranded breaks, and transfers the ADP-ribose moiety of NAD to nuclear proteins. The activation of ADPRP is important for DNA repair and replication, and also has been postulated to play a role in the pathogenesis of lymphocyte ...
H, Yamanaka, E H, Willis, C A, Penning, C L, Peebles, E M, Tan, D A, Carson   +5 more
openaire   +3 more sources

Latin American Challenges and Recommendations for Poly Adenosine Diphosphate Ribose Polymerase Inhibitor Treatment in Metastatic Castration Resistant Prostate Cancer: An Expert Overview [PDF]

Cancer Control
In Latin America, prostate cancer is the third most common cancer overall and the most common in men, with the highest mortality rate of all cancers.
Rodolfo Borges dos Reis MD, PHD, José L. Aguilar-Ponce MD, Federico Cayol MD, MSc, Angela M. Jansen PhD, MHS, Ray Manneh K MD, MSc, Tomas R Merino MD, Gayatri Sanku PhD, MPH, Laura B. Vaca MD, Pedro Isaacsson Velho MD, Ernesto P. Korbenfeld MD   +9 more
doaj   +2 more sources

Kinetic and Static Analysis of Poly-(Adenosine Diphosphate-Ribose) Polymerase-1-Targeted ¹⁸F-Fluorthanatrace PET Images of Ovarian Cancer. [PDF]

J Nucl Med, 2022
Young AJ, Pantel AR, Viswanath V, Dominguez TL, Makvandi M, Lee H, Li S, Schubert EK, Pryma DA, Farwell MD, Mach RH, Simpkins F, Lin LL, Mankoff DA, Doot RK.   +14 more
europepmc   +3 more sources

Programmed death ligand 1, poly adenosine diphosphate ribose polymerase, and vascular endothelial growth factor receptor inhibition: a potential combination regimen for targeting triple-negative breast cancer? [PDF]

Int J Surg, 2023
Abdul Wahid M, Hussain HU, Ghouri H, Khan T, Rehan ST, Mumtaz H.   +5 more
europepmc   +2 more sources

Novel treatment strategies in triple-negative breast cancer: specific role of poly(adenosine diphosphate-ribose) polymerase inhibition [PDF]

Pharmacogenomics and Personalized Medicine, 2014
M William Audeh Division of Medical Oncology, Samuel Oschin Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA Abstract: Inhibitors of the poly(adenosine triphosphate-ribose) polymerase (PARP)-1 enzyme induce synthetic lethality in ...
Audeh MW
doaj   +2 more sources

Do Not Forget Poly (Adenosine Diphosphate-Ribose) Polymerase Inhibitors in Ovarian Carcinosarcoma. [PDF]

Cureus, 2022
Magalhães D, Bartosch C, Abreu MH.
europepmc   +3 more sources

The poly(adenosine diphosphate-ribose) polymerase inhibitor PJ34 reduces pulmonary ischemia-reperfusion injury in rats. [PDF]

Transplantation, 2014
Hatachi G, Tsuchiya T, Miyazaki T, Matsumoto K, Yamasaki N, Okita N, Nanashima A, Higami Y, Nagayasu T.   +8 more
europepmc   +3 more sources

Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: lessons learned from its inhibitors. [PDF]

Oncotarget, 2017
Cseh AM, Fábián Z, Sümegi B, Scorrano L.   +3 more
europepmc   +3 more sources

Positron Emission Tomography Imaging of Poly-(Adenosine Diphosphate-Ribose) Polymerase 1 Expression in Breast Cancer: A Nonrandomized Clinical Trial. [PDF]

JAMA Oncol, 2020
McDonald ES, Doot RK, Pantel AR, Farwell MD, Mach RH, Maxwell KN, Mankoff DA.   +6 more
europepmc   +2 more sources

Kinetic Analysis and Metabolism of Poly(Adenosine Diphosphate-Ribose) Polymerase-1-Targeted ¹⁸F-Fluorthanatrace PET in Breast Cancer. [PDF]

J Nucl Med
Young AJ, Pantel AR, Kiani M, Doot RK, Bagheri S, Pryma DA, Farwell MD, Li S, Lee H, Schubert EK, Secreto A, Zuckerman SP, Nayak A, Choi H, Carlin S, DeMichele A, Mankoff DA, Zhou R, Mach RH, McDonald ES.   +19 more
europepmc   +3 more sources