Results 21 to 30 of about 3,094 (198)

Tankyrase Regulates Neurite Outgrowth through Poly(ADP-ribosyl)ation-Dependent Activation of β-Catenin Signaling [PDF]

open access: yesInternational Journal of Molecular Sciences, 2022
Hiroyuki Nakamura   +2 more
exaly   +2 more sources

Poly(ADP-ribosyl)ation associated changes in CTCF-chromatin binding and gene expression in breast cells. [PDF]

open access: hybridBiochim Biophys Acta Gene Regul Mech, 2018
Pavlaki I   +7 more
europepmc   +2 more sources

PARP3 supervises G9a-mediated repression of adhesion and hypoxia-responsive genes in glioblastoma cells

open access: yesScientific Reports, 2022
In breast cancer, Poly(ADP-ribose) polymerase 3 (PARP3) has been identified as a key driver of tumor aggressiveness exemplifying its selective inhibition as a promising surrogate for clinical activity onto difficult-to-treat cancers. Here we explored the
Leonel Nguekeu-Zebaze   +6 more
doaj   +1 more source

Plants get on PAR with poly(ADP-ribosyl)ation. [PDF]

open access: yesEMBO Rep, 2016
Poly(ADP‐ribosyl)ation, or PARylation, was first described over 50 years ago. Since then, our understanding of the biochemistry and enzymology of this protein modification has significantly progressed. PARylation has long been associated with DNA damage and DNA repair as well as genotoxic stress [1], [2].
Menke FL.
europepmc   +4 more sources

PARP1 Regulates the Biogenesis and Activity of Telomerase Complex Through Modification of H/ACA-Proteins

open access: yesFrontiers in Cell and Developmental Biology, 2021
Poly(ADP-ribose) polymerase 1 (PARP1) is established as a key regulator of the cellular DNA damage response and apoptosis. In addition, PARP1 participates in the global regulation of DNA repair, transcription, telomere maintenance, and inflammation ...
Nikita V. Savelyev   +10 more
doaj   +1 more source

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