A biocompatible polylactide-ε-caprolactone polymer coated with poly(hexamethylene biguanide) displays antibacterial properties against slime-producing S. epidermidis [PDF]
Introduction: produced by renewable resources, biodegradable polymers with their competitive mechanical properties, thermal stability and biocompatibility are important alternatives to other synthetic materials for use in medical devices, i.e ...
Becker-Willinger, Carsten +7 more
core +3 more sources
Poly (hexamethylene biguanide), adsorbed onto Ti-Al-V alloys, kills slime-producing Staphylococci and Pseudomonas aeruginosa without inhibiting SaOs-2 cell differentiation. [PDF]
Antimicrobial coating of implant material with poly(hexamethylene biguanide) hydrochloride (PHMB) may be an eligible method for preventing implant-associated infections.
M. Hornschuh +5 more
semanticscholar +4 more sources
Regenerated silk fibers were fabricated through dry-wet spinning process using N-methyl morpholine N-oxide and methanol as solvent and coagulant, respectively. Several concentrations of poly (hexamethylene) biguanide (PHMB) (0.27, 0.41, and 0.55 mL per 1
Seyedeh Ameneh Siadat, Javad Mokhtari
doaj +3 more sources
Physical and Chemical Characterization of Poly(hexamethylene biguanide) Hydrochloride [PDF]
We present the characterization of commercially available Poly(hexamethylene biguanide) hydrochloride (PHMB), a polymer with biocidal activity and several interesting properties that make this material suitable as a building block for supramolecular ...
G. F. Paula +2 more
semanticscholar +2 more sources
Improved Adsorption of the Antimicrobial Agent Poly (Hexamethylene) Biguanide on Ti-Al-V Alloys by NaOH Treatment and Impact of Mass Coverage and Contamination on Cytocompatibility [PDF]
Unlike the native surface of the implant material (Ti6Al4V), oxidation with H2O2 leads to increased binding of the effective antimicrobial agent poly(hexamethylene) biguanide [PHMB]. However, treating with NaOH instead results in an even higher PHMB mass
P. Zwicker +10 more
semanticscholar +2 more sources
Polyhexanide and chlorhexidine loaded chitosan wound dressings [PDF]
in proceedings of the Fourth International Congress of CiiEM: Health, Well-Being and Ageing in the 21st Century, held at Egas Moniz’ University Campus in Monte de Caparica, Almada, from 3–5 June 2019.This is an Open Access article distributed under the ...
Nydrioti E, Saramago B, Serro A.
europepmc +3 more sources
Surgical sutures are widely utilized medical devices for the purpose of closing wounds after surgical interventions. During surgical procedures, sutures can come into contact with microorganisms in the surrounding environment, leading to the development ...
O. Bozkaya +3 more
semanticscholar +2 more sources
Cellular gene delivery via poly(hexamethylene biguanide)/pDNA self-assembled nanoparticles. [PDF]
Cellular gene delivery via polycations has wide implications for the potential of gene therapy, but it has remained a challenge due to the plethora of pre- and post-uptake barriers that must be overcome to reach desired efficiency. Herein we report poly(hexamethylene biguanide) (PHMB) as a nano-vector for intracellular delivery of plasmid DNA (pDNA ...
Alexandru Chivu +6 more
semanticscholar +4 more sources
Comparison of the in vitro antibiofilm activities of otic cleansers against canine otitis externa pathogens. [PDF]
Background – Biofilm production by canine otitis externa (COE) pathogens and resistance development to multiple antimicrobials are commonly reported problems in veterinary practice. The use of adjuvants to disrupt biofilms may be a viable adjunctive therapy.
Savaliya BF, Kim S, Veltman T, Trott DJ.
europepmc +2 more sources
Bactericidal Activity and Physiological Effects of Combined Application of Poly-Hexamethylene Biguanide Hydrochloride and 1-bromo-3-chloro-5, 5-dimethylimidazolidine-2, 4-dione on Staphylococcus aureus [PDF]
Poly-hexamethylene biguanide hydrochloride (PHMB) and 1-bromo-3chloro-5,5-dimethylimidazolidine-2,4dione (BCDMH) are widely used for surface disinfection.
W. Huai, Z. Deng, Qin Chen
semanticscholar +2 more sources

