The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile +41 more
core +3 more sources
Green Advances in Wet Finishing Methods and Nanoparticles for Daily Textiles. [PDF]
This overview presented nanoparticles (NPs) as a potential green alternative to hazard chemicals in wet textile finishing to provide antibacterial, flame, water, and UV protection. Upgrades to traditional processes included more innovative eco‐friendly technology to improve textile/NPs adhesion and product durability.
Patti A.
europepmc +2 more sources
Electrospun biodegradable polymers loaded with bactericide agents [PDF]
Development of materials with an antimicrobial activity is fundamental for different sectors, including medicine and health care, water and air treatment, and food packaging.
Franco García, María Lourdes +3 more
core +2 more sources
Development and experimental validation of an overlay mortar with biocide activity [PDF]
Biodeterioration of concrete by microorganism colonisation may be a problem in several structures, especially in irrigation and hydroelectric canals.
Aguado de Cea, Antonio +4 more
core +2 more sources
Poly (hexamethylene biguanide), adsorbed onto Ti-Al-V alloys, kills slime-producing Staphylococci and Pseudomonas aeruginosa without inhibiting SaOs-2 cell differentiation [PDF]
Antimicrobial coating of implant material with poly(hexamethylene biguanide) hydrochloride (PHMB) may be an eligible method for preventing implant-associated infections.
Finke, Birgit +5 more
core +1 more source
Antimicrobial activity of poly(ester urea) electrospun fibers loaded with bacteriophages [PDF]
The capacity to load bacteriophages into electrospun nanofibers of two representative biocompatible polymers has been evaluated, paying special attention to the possibility of preserving their antibacterial activity.
Casas Becerra, María Teresa +6 more
core +3 more sources
Update on the role of antiseptics in the management of chronic wounds with critical colonisation and/or biofilm [PDF]
Biofilms play a major role in delaying chronic wounds from healing. A wound infiltrated with biofilm, or “critically colonised” wound, may become clinically infected if the number of microbes exceeds a critical level.
Alves, Paulo J. +5 more
core +2 more sources
PHB-PEO electrospun fiber membranes containing chlorhexidine for drug delivery applications [PDF]
Fiber meshes of poly(hydroxybutyrate) (PHB) and poly(hydroxybutyrate)/poly(ethylene oxide) (PHB/PEO) with different concentrations of chlorhexidine (CHX) were prepared by electrospinning for assessment as a polymer based drug delivery system.
A.A.o.T.C.a. Colorists +46 more
core +1 more source
Cellular gene delivery via poly(hexamethylene biguanide)/pDNA self-assembled nanoparticles [PDF]
Cellular gene delivery via polycations has wide implications for the potential of gene therapy, but it has remained a challenge due to the plethora of pre- and post-uptake barriers that must be overcome to reach desired efficiency.
An, A +6 more
core
Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles
The siRNA transfection efficiency of nanoparticles (NPs), composed of a superparamagnetic iron oxide core modified with polycationic polymers (poly(hexamethylene biguanide) or branched polyethyleneimine), were studied in CHO‐K1 and HeLa cell lines. Both NPs demonstrated to be good siRNA transfection vehicles, but unmodified branched polyethyleneimine ...
Betzaida Castillo +8 more
wiley +1 more source

