Results 101 to 110 of about 20,627 (136)
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Arzneimittel-Forschung, 1986
A new procedure for covalent immobilization of polyriboinosinic-polyribocytidylic acid (poly I:C) on the surface of polymethylmethacrylate (PMMA) is described. Carboxyl groups are generated on the PMMA surface and react with primary amino groups of cytosine. These amino groups are made accessible by heating.
H, Hydén, K, Holmberg
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A new procedure for covalent immobilization of polyriboinosinic-polyribocytidylic acid (poly I:C) on the surface of polymethylmethacrylate (PMMA) is described. Carboxyl groups are generated on the PMMA surface and react with primary amino groups of cytosine. These amino groups are made accessible by heating.
H, Hydén, K, Holmberg
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Phase I Trial with the Interferon Inducer Poly I:C/Poly-L-Lysine (Poly ICL)
Journal of Interferon Research, 1983Poly I:C/poly-L-lysine (poly ICL) was previously shown to be a potent inducer of interferon (IFN) production in nonhuman primates. In this limited trial in five patients with advanced cancer, poly ICL stimulated primarily leukocyte interferon (IFN-α) with peak titers of 40 to 160 units/ml, usually at 24 hours after poly ICL administration.
S.E. KROWN +5 more
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Effect of poly I:C on cell proliferation in vivo.
Archivum immunologiae et therapiae experimentalis, 1978Female Swiss albino mice were injected intraperitoneally with poly I:C1 microgram/g body weight. The animals were killed 2, 12, and 24 hr after the injection of poly I:C. Half an hour before the death of animals they were reinjected intraperitoneally with 3H-thymidine. Fragments of ileum were excised.
M, Kobus, W, Sawicki, M, Korbecki
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Differences in the B Cell Interferon Responses to Lipopolysaccharide and Poly I:C
Journal of Interferon Research, 1981Two polyclonal B cell activators, lipopolysaccharide (LPS) and poly I:C, have been used to induce interferon (IFN) production by murine B cell populations. The results show that splenic B cell-enriched fractions, isolated by wheat germ agglutination followed by C-dependent anti-Thy 1.2 cytolysis, respond to treatment with poly I:C + DEAE-dextran by IFN
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VEGF, Poly(i:C), and Innate Immune Response
American Journal of Respiratory and Critical Care Medicine, 2012Laimute, Taraseviciene-Stewart +1 more
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Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression
Nature Reviews Molecular Cell Biology, 2021Lori Anne Passmore, Jeff Coller
exaly
Effects of poly I:C in porcine iron deficient neutropenia.
The Cornell veterinarian, 1985Withholding iron dextran treatment normally given to pigs at 1-3 days of age to prevent anemia resulted also in neutropenia. Polyinosinic acid:polycytidylic acid (poly I:C) at 0.5 mg/kg IV at 25 days of age resulted in induction of putative interferon 2 to 24 hours later, with significantly (P less than 0.05) lower concentrations in iron-deficient (Fe-)
J H, Gainer, J, Guarnieri
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Particulate formulations for the delivery of poly(I:C) as vaccine adjuvant.
2013Current research and development of antigens for vaccination often center on purified recombinant proteins, viral subunits, synthetic oligopeptides or oligosaccharides, most of them suffering from being poorly immunogenic and subject to degradation.
Hafner AM, Corthésy B, Merkle HP
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Response of bronchial and alveolar epithelial cells to poly (I:C)
Mechanisms of lung injury and repair, 2023Nafeesa Shahdab +4 more
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