Results 1 to 10 of about 104,144 (317)
Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification [PDF]
eLife, 2020 Understanding genome organization and gene regulation requires insight into RNA transcription, processing and modification. We adapted nanopore direct RNA sequencing to examine RNA from a wild-type accession of the model plant Arabidopsis thaliana and a ...
Matthew T Parker +8 more
doaj +5 more sources
Analysis of RNA Transcribed by RNA Polymerase III from B2 SINEs in Mouse Cells [PDF]
Non-Coding RNABackground/Objectives: SINEs (short interspersed elements) are eukaryotic non-autonomous retrotransposons. They are transcribed by RNA polymerase III (pol III) and generate non-coding RNAs.
Olga R. Borodulina +4 more
doaj +2 more sources
Comprehensive profiling of rhizome-associated alternative splicing and alternative polyadenylation in moso bamboo (Phyllostachys edulis). [PDF]
The Plant Journal, 2017 Moso bamboo (Phyllostachys edulis) represents one of the fastest-spreading plants in the world, due in part to its well-developed rhizome system. However, the post-transcriptional mechanism for the development of the rhizome system in bamboo has not been
Cai, Dawei +8 more
core +2 more sources
Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3′ end biogenesis
eLife, 2022 3′ end formation of most eukaryotic mRNAs is dependent on the assembly of a ~1.5 MDa multiprotein complex, that catalyzes the coupled reaction of pre-mRNA cleavage and polyadenylation. In mammals, the cleavage and polyadenylation specificity factor (CPSF)
Lena Maria Muckenfuss +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Better methods to interrogate host-pathogen interactions during Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infections are imperative to help understand and prevent this disease.
Jessie J.-Y. Chang +15 more
doaj +1 more source
Insects, 2022 During the messenger RNA (mRNA) maturation process, RNA polyadenylation is a key step, and is coupled to the termination of transcription. Various cis-acting elements near the cleavage site and their binding factors would affect the process of ...
Liying Fang +4 more
doaj +1 more source
The transcriptional elongation rate regulates alternative polyadenylation in yeast
eLife, 2020 Yeast cells undergoing the diauxic response show a striking upstream shift in poly(A) site utilization, with increased use of ORF-proximal poly(A) sites resulting in shorter 3’ mRNA isoforms for most genes.
Joseph V Geisberg +2 more
doaj +1 more source
RNA Unwinding by the Trf4/Air2/Mtr4 Polyadenylation (TRAMP) Complex [PDF]
, 2012 Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p.
Anderson, James T. +3 more
core +2 more sources
Virology Journal, 2019 Background Polyadenylation influences many aspects of mRNA as well as viral RNA. variable polyadenylation at the 3' end have been reported in RNA viruses.
Guowei Geng +3 more
doaj +1 more source
Mitochondrial Polyadenylation Is a One-Step Process Required for mRNA Integrity and tRNA Maturation. [PDF]
PLoS Genetics, 2016 Polyadenylation has well characterised roles in RNA turnover and translation in a variety of biological systems. While polyadenylation on mitochondrial transcripts has been suggested to be a two-step process required to complete translational stop codons,
Ana Bratic +8 more
doaj +1 more source