Frontiers in Chemistry, 2020 Naphthalimides, such as amonafide and mitonafide in clinical trials, have been developed as antitumor agents for orthotopic tumor. However, the serious side effects in cancer patients limit their applications.
Jing Ma +18 more
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Exogén SA kezelések fényben és sötétben történő hatásának összehasonlító elemzése vad típusú és etilén receptor mutáns, Never-ripe paradicsom növények leveleiben [PDF]
, 2018 Biotic stresses is caused in plants due to damage instigated by other organisms, like insects, disease (fungal, bacterial, and viral), which are major limitations to crop yield. The cellular response to biotic stress is an oxidative and nitrosative burst
Takács Zoltán
core
Perturbation of spermine synthase Gene Expression and Transcript Profiling Provide New Insights on the Role of the Tetraamine Spermine in Arabidopsis Defense against Pseudomonas viridiflava1[C][W] [PDF]
, 2011 The role of the tetraamine spermine in plant defense against pathogens was investigated by using the Arabidopsis (Arabidopsis thaliana)-Pseudomonas viridiflava pathosystem.
Blázquez, Miguel Angel +7 more
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Bis(benzyl)polyamine analogs as novel substrates for polyamine oxidase.
Journal of Biological Chemistry, 1990 N,N'-Bis(benzyl)polyamine analogs were found to be substrates for highly purified polyamine oxidase. Metabolism of these analogs was apparently dependent on molecular O2 and resulted in the formation of benzaldehyde, H2O2, and a polyamine analog with free terminal amines.
A J, Bitonti +5 more
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The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Lean mice and DIO mice were fed either a low‐fat maintenance diet (MD) or a high‐fat obesogenic diet (OD) during pegylated asparaginase exposure. OD exacerbated asparaginase‐induced weight loss and modestly increased liver triglycerides and ER stress in lean mice.
Chintan T. Bhavsar +9 more
wiley +1 more source
Comparative transcriptional profiling of orange fruit in response to the biocontrol yeast Kloeckera apiculata and its active compounds [PDF]
, 2016 List of defence-related differentially expressed genes in citrus under K. apiculata treatment.
Chao-an Long +4 more
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Superoxide Radical Dismutation as New Therapeutic Strategy in Parkinson’s Disease [PDF]
, 2017 open4siAging is the biggest risk factor for developing many neurodegenerative disorders, including idiopathic Parkinson's disease (PD). PD is still an incurable disorder and the available medications are mainly directed to the treatment of symptoms in ...
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Biologia Plantarum, 2019 Sucrose, proline, and polyamines are compatible solutes accumulating in plant tissues and increasing cellular osmolarity under environmental stresses. These compatible solutes and hydrogen peroxide can function as signaling molecules in plants. There has
C. Altuntaş +5 more
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Macrophage depletion reduces postsurgical tumor recurrence and metastatic growth in a spontaneous murine model of melanoma [PDF]
, 2015 International audienceSurgical resection of tumors is often followed by regrowth at the primary site and metastases may emerge rapidly following removal of the primary tumor.
Abastado, Jean-Pierre +6 more
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Scientific ReportsPolyamines (putrescine, spermidine, and spermine) are among the most abundant intracellular small molecular metabolites, with concentrations at the mM level. The ratios of these three molecules remain constant under physiological conditions. Stress (i.e.
Tomoaki Hirakawa +7 more
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