Results 131 to 140 of about 86,841 (327)

Design and Synthesis of Polyamine‐Proteolysis Targeting Chimera Conjugates for Histone Deacetylase (HDAC) Degradation with Enhanced Cellular Uptake

ChemistryOpen, EarlyView.
In this article, proteolysis targeting chimeras (PROTACs) bearing a polyamine linker capable of crossing cancer cell membranes via the polyamine transport system are synthesized and evaluated. The results provide valuable insights for the design of PROTACs with enhanced cellular uptake efficiency.
Yanran Liu, Wentian Chen, Yanwei Shang, Chaonan Tang, Xianming Zeng, Jun Li, Wenting Du   +6 more
wiley   +1 more source

Enhancement of Ureaplasma urealyticum growth on a differential agar medium (A7B) by a polyamine, putrescine [PDF]

, 1979
Maurice C. Shepard, R S Combs
openalex   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Rapid Mechanochemical Synthesis of Oxyhalide Superionic Conductor: Time‐Resolved Structural Evolution

Small Methods, EarlyView.
Time‐resolved synchrotron X‐ray scattering coupled with mechanochemical synthesis reveals the structural evolution of oxyhalide superionic conductors. Oxygen incorporation governs reaction kinetics, amorphization, and microstructural transformations, while enabling efficient Li‐ion diffusion. This study highlights critical correlations between reaction
Denys Butenko, Jo‐chi Tseng, Xinyu Zhang, Pencheng Yu, Wen Tang, Jiuwei Lei, Shuoxiao Zhang, Pengfei Wang, Yuhang Li, Ming Liu, Wen Yin, Liping Wang, Songbai Han, Wei Xia, Yusheng Zhao, Jinlong Zhu   +15 more
wiley   +1 more source

Effect of Additives on CO2 Adsorption of Polyethylene Polyamine-Loaded MCM-41 [PDF]

Xia Wang, Wu-Lan Zeng, Peidan Hu, Shengxin Liu, Yuechao Lin, Zhaowen He, Chunling Xin, Xiangjun Kong, Jinghan Xu   +8 more
openalex   +1 more source

Life without putrescine: disruption of the gene-encoding polyamine oxidase in Ustilago maydis odc mutants [PDF]

, 2010
Laura Valdés‐Santiago, Doralinda Guzmán-de-Peña, José Ruíz-Herrera   +2 more
openalex   +1 more source

Exploring the impact of microbial dysbiosis on ovarian cancer and the therapeutic potential of probiotics

VIEW, EarlyView.
Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li, Nalan Tu, Xin Ning, Yunyan Cong, Fei Wu, Xiuli Zhang, Runrong Li, Yue Xu, Binqiao Wang, Liqin Jin, Yuanming Shen, Jihong Liu   +11 more
wiley   +1 more source

Azotobacter vinelandii RNA polymerase. II - Effect of ribonuclease on polymerase activity [PDF]

Ribonuclease effect on polymerase activity during ribonucleic acid synthesis ...
Krakow, J. S.
core   +1 more source

Transmembrane ion transport mediated by amphiphilic polyamine dendrimers

, 1997
Naomi Sakai, Stefan Matile
openalex   +1 more source

Combination therapy with 2‐difluoromethylornithine and a polyamine transport inhibitor against murine squamous cell carcinoma [PDF]

, 2005
Yan Chen, Reitha S. Weeks, Mark R. Burns, David W. Boorman, Andres J. Klein–Szanto, Thomas G. O’Brien   +5 more
openalex   +1 more source