N8‐Modified Quino[4,3,2‐Kl]acridines as Promising Antimalarial G‐Quadruplex Ligands
A series of extended aromatic compounds with tunable substituents was synthesized using a multistep methodology which allows various substitutions of the 8H‐quino[4,3,2‐kl]acridine scaffold. This chemical series appeared as a promising way to new antimalarial drug candidates with high activity (IC50 < 100 nM), exhibiting a novel mechanism of action ...
Steve Saulnier +10 more
wiley +1 more source
Circulating Polyamines and Metabolic Changes Following a Mediterranean Diet with or Without Naltrexone/Bupropion in Breast Cancer Survivors: An Exploratory Secondary Analysis. [PDF]
Choi WJ +6 more
europepmc +1 more source
Metal‐Free Ligand‐Centered Radical Scavenging in Pyridine‐Modified Tetraaza Macrocycles
Ligand‐centered hydrogen‐atom transfer in pyridinophane macrocycles generates delocalized radicals, with Py2N2 enabling cooperative captodative stabilization and enhanced DPPH• quenching. Pyridine‐modified tetraaza macrocycles are widely studied as ligand platforms for metal coordination, yet their intrinsic redox and radical reactivity in the absence ...
Christina Mantsorov +9 more
wiley +1 more source
In vitro effect of fresh and frozen seminal plasma on the proliferation and viability of periodontal ligament fibroblasts. [PDF]
Cano SVO +3 more
europepmc +1 more source
Polyamines as a Universal Language of Host-Microbiota Symbiosis. [PDF]
Fang X, Guo Y, Huang J, Zhang M.
europepmc +1 more source
The remarkable legacy of the K6/ODC mouse: mechanisms of polyamine-promoted tumorigenesis revealed. [PDF]
Gilmour SK.
europepmc +1 more source
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti +8 more
wiley +1 more source
Amino Oxidase Hard Protein Corona with Metabolic-Triggered Intracellular Biocatalysis. [PDF]
Tonolo F +12 more
europepmc +1 more source
Ionic epoxy networks are prepared using ammonium salts as hardeners, leading to a two‐stage curing process with a thermoplastic‐like intermediate. This uncommon behavior enables extrusion and fabrication of thermoplastic prepregs that can be cured into thermoset composites.
Izabela Kurowska +10 more
wiley +1 more source
ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis. [PDF]
van Veen S +23 more
europepmc +1 more source

