Results 191 to 200 of about 44,703 (290)

N8‐Modified Quino[4,3,2‐Kl]acridines as Promising Antimalarial G‐Quadruplex Ligands

open access: yesChemBioChem, Volume 27, Issue 17, 14 September 2026.
A series of extended aromatic compounds with tunable substituents was synthesized using a multistep methodology which allows various substitutions of the 8H‐quino[4,3,2‐kl]acridine scaffold. This chemical series appeared as a promising way to new antimalarial drug candidates with high activity (IC50 < 100 nM), exhibiting a novel mechanism of action ...
Steve Saulnier   +10 more
wiley   +1 more source

Metal‐Free Ligand‐Centered Radical Scavenging in Pyridine‐Modified Tetraaza Macrocycles

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 34, 11 September 2026.
Ligand‐centered hydrogen‐atom transfer in pyridinophane macrocycles generates delocalized radicals, with Py2N2 enabling cooperative captodative stabilization and enhanced DPPH• quenching. Pyridine‐modified tetraaza macrocycles are widely studied as ligand platforms for metal coordination, yet their intrinsic redox and radical reactivity in the absence ...
Christina Mantsorov   +9 more
wiley   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

open access: yesAdvanced Materials, Volume 38, Issue 51, 11 September 2026.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti   +8 more
wiley   +1 more source

Amino Oxidase Hard Protein Corona with Metabolic-Triggered Intracellular Biocatalysis. [PDF]

open access: yesInt J Mol Sci
Tonolo F   +12 more
europepmc   +1 more source

Ammonium Salts as Curing Agents to Obtain Ionic Epoxy Resins With a Thermoplastic‐to‐Thermoset Transition

open access: yesAdvanced Materials, Volume 38, Issue 51, 11 September 2026.
Ionic epoxy networks are prepared using ammonium salts as hardeners, leading to a two‐stage curing process with a thermoplastic‐like intermediate. This uncommon behavior enables extrusion and fabrication of thermoplastic prepregs that can be cured into thermoset composites.
Izabela Kurowska   +10 more
wiley   +1 more source

ATP13A4 gates extracellular polyamine levels to control excitatory synaptogenesis. [PDF]

open access: yesNat Commun
van Veen S   +23 more
europepmc   +1 more source

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