Results 31 to 40 of about 44,703 (290)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Novel Insight into the Multiple Biological Characteristics of Polyamines in the Gut: From Structure to Function

Frontiers in Bioscience-Landmark
This review explores the structure of polyamines, including putrescine, spermidine, and spermine, and their crucial roles in immune cell functions. Polyamines are active compounds derived from ornithine that regulate signaling pathways by interacting ...
Xinyi Yu, Shuzi Xin, Xiaohui Liu, Luming Pan, Weikai Shi, Yize Li, Hongli Wang, Xin Lu, Han Gao, Jingdong Xu   +9 more
doaj   +1 more source

Acetoacetates Derived From Vegetable Oils: A Platform for Tailor‐Made Vinylogous Urethane Foams

Advanced Functional Materials, EarlyView.
A renewable vegetable oil is converted into acetoacetate‐functionalized precursors for the preparation of catalyst‐free vinylogous urethane foams. Room‐temperature foaming with n‐pentane generates lightweight cellular materials, while the choice of amine enables control over foam structure and mechanical properties.
Krzysztof Polaczek, Priscilla de Souza Lima, Olga Gotkiewicz, Ondrej Kopilec, Radka Hobzova, Lívia Kanizsová, Mikelis Kirpluks, Ondrej Sedlacek, Hynek Beneš   +8 more
wiley   +1 more source

Polyamines mediate cellular energetics and lipid metabolism through mitochondrial respiration to facilitate virus replication.

PLoS Pathogens
Polyamines are critical cellular components that regulate a variety of processes, including translation, cell cycling, and nucleic acid metabolism. The polyamines, putrescine, spermidine, and spermine, are found abundantly within cells and are positively-
Yazmin E Cruz-Pulido, Natalie J LoMascolo, Delaina May, Jomana Hatahet, Caroline E Thomas, Andrea K W Chu, Samantha P Stacey, Maria Del Mar Villanueva Guzman, Gregory Aubert, Bryan C Mounce   +9 more
doaj   +1 more source

Mechanism Exploration of the Effect of Polyamines on the Polishing Rate of Silicon Chemical Mechanical Polishing: A Study Combining Simulations and Experiments

Nanomaterials
Polyamines have become important chemical components used in several integrated circuit manufacturing processes, such as etching, chemical mechanical polishing (CMP), and cleaning.
Ziwei Lin, Junli Zhu, Qi Huang, Lei Zhu, Weimin Li, Wenjie Yu   +5 more
doaj   +1 more source

Practical Synthesis of Polyamine Succinamides and Branched Polyamines

ChemistryOpen, 2022
AbstractAntibiotic resistance is now a growing threat to human health, further exacerbated by the lack of new antibiotics. We describe the practical synthesis of a series of substituted polyamine succinamides and branched polyamines that are potential new antibiotics against both Gram‐positive and Gram‐negative bacteria, including MRSA and Pseudomonas ...
Abdulaziz H. Alkhzem, Maisem Laabei, Timothy J. Woodman, Ian S. Blagbrough   +3 more
openaire   +4 more sources

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

Effects of polyamines on Vibrio cholerae virulence properties. [PDF]

PLoS ONE, 2013
Vibrio cholerae is the causative agent of the severe enteric disease cholera. To cause cholera the bacterium must be able to synthesize both cholera toxin (CT) and toxin-coregulated pilus (TCP) which mediates autoagglutination and is required for ...
John Bradley Goforth, Nicholas Emmanuel Walter, Ece Karatan   +2 more
doaj   +1 more source

Improvement of plant regeneration efficiency using polyamines for double haploid production in wheat (Triticum aestivum)

The Indian Journal of Agricultural Sciences, 2022
Polyamines are low molecular weight nitrogen containing compounds present in all living organisms. These are considered to be a new class of plant hormones, and play a positive role in plant growth and developmental processes including cell division, in
PRINKA GOYAL, S K THIND, PUJA SRIVASTAVA, ACHLA SHARMA   +3 more
doaj   +1 more source

Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy

Medical Sciences, 2022
Polyamines are small polycationic alkylamines involved in many fundamental cellular processes, including cell proliferation, survival, and protection from oxidative stress. Polyamine homeostasis is tightly regulated through coordinated biosynthesis, catabolism, and transport.
Cassandra E. Holbert, Jackson R. Foley, Ao Yu, Tracy Murray Stewart, Otto Phanstiel, David Oupicky, Robert A. Casero   +6 more
openaire   +3 more sources