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Polyamines are small organic compounds found in all living organisms. According to the high degree of positive charge at physiological pH, they interact with negatively charged macromolecules, such as DNA, RNA, and proteins, and modulate their activities.
Taku Takahashi
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The polyamines spermine, spermidine, and putrescine are involved in various biological processes, notably in cell proliferation and differentiation, and also have antioxidant properties.
Nelly C. Muñoz-Esparza +15 more
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Polyamines and apoptosis [PDF]
The natural polyamines putrescine, spermidine and spermine are in multiple ways involved in cell growth and the maintenance of cell viability. In the course of the last 15 years more and more evidence hinted also at roles in gene regulation. It is therefore not surprising that the polyamines are involved in events inherent to genetically programmed ...
Nikolaus, Seiler, Francis, Raul
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Free and Cell Wall-Bound Polyamines under Long-Term Water Stress Applied at Different Growth Stages of ×Triticosecale Wittm. [PDF]
Long-stemmed and semi-dwarf cultivars of triticale were exposed to water stress at tillering, heading and anthesis stage. Quantitative determination of free and cell wall-bound polyamines, i.e.
Tomasz Hura +4 more
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Role of Polyamines in Asthma Pathophysiology
Asthma is a complex disease of airways, where the interactions of immune and structural cells result in disease outcomes with airway remodeling and airway hyper-responsiveness.
Vaibhav Jain
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The role of polyamines in response to abiotic stresses [PDF]
Under the influence of various abiotic stresses, the growth, development and geographic distribution of plants change. In order to survive adverse environmental conditions and to sustain life, plants have evolved various combat and adaptive strategies to
Saeed Amini, Reza Maali Amiri
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Metabolism is key to cellular processes that underlie the ability of a virus to productively infect. Polyamines are small metabolites vital for many host cell processes including proliferation, transcription, and translation.
Mason R Firpo +4 more
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Influence of anti-hyperlipidemic activity by co-administration of polyamines and rutin with simvastatin [PDF]
Introduction: Natural polyphenols, rutin, endogenous polycations, and polyamines (spermine and spermidine) are reported to have beneficial effects on hyperlipidemia, obesity, and cardiovascular disease (CVD).
Rajesh R Patil +3 more
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Polyamines as redox homeostasis regulators during salt stress in plants
The balance between accumulation of stress-induced polyamines and reactive oxygen species (ROS) is arguably a critical factor in plant tolerance to salt stress.
Jayita eSaha +7 more
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The high-yielding production of pharmaceutically significant secondary metabolites in filamentous fungi is obtained by random mutagenesis; such changes may be associated with shifts in the metabolism of polyamines.
Alexander A. Zhgun, Mikhail A. Eldarov
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