Autosomal dominant polycystic kidney disease and coronary artery dissection or aneurysm: A systematic review [PDF]
, 2016 Importance Autosomal dominant polycystic kidney disease (ADPKD) has been associated with cardiovascular abnormalities such as intracranial and aortic aneurysms.
Lopes, JA, Neves, JB, Rodrigues, FB
core +1 more source
PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy
eLifeHIV disease remains prevalent in the USA and chronic kidney disease remains a major cause of morbidity in HIV-1-positive patients. Host double-stranded RNA (dsRNA)-activated protein kinase (PKR) is a sensor for viral dsRNA, including HIV-1.
Teruhiko Yoshida +16 more
doaj +1 more source
The Open Kidney Ultrasound Data Set [PDF]
arXiv, 2022 Ultrasound, because of its low cost, non-ionizing, and non-invasive characteristics, has established itself as a cornerstone radiological examination. Research on ultrasound applications has also expanded, especially with image analysis with machine learning. However, ultrasound data are frequently restricted to closed data sets, with only a few openly
arxiv
Treatment of chronic kidney diseases with histone deacetylase inhibitors
Frontiers in Physiology, 2015 Histone deacetylases (HDACs) induce deacetylation of both histone and non-histone proteins and play a critical role in the modulation of physiological and pathological gene expression.
Na Liu, S. Zhuang
semanticscholar +1 more source
European ADPKD Forum multidisciplinary position statement on autosomal dominant polycystic kidney disease care [PDF]
, 2017 Autosomal dominant polycystic kidney disease (ADPKD) is a chronic, progressive condition characterised by the development and growth of cysts in the kidneys and other organs and by additional systemic manifestations.
Alastair Kent +22 more
core +6 more sources
Molecular and cellular pathogenesis of autosomal recessive polycystic kidney disease
Brazilian Journal of Medical and Biological Research, 2006 Autosomal recessive polycystic kidney disease (ARPKD) is an inherited disease characterized by a malformation complex which includes cystically dilated tubules in the kidneys and ductal plate malformation in the liver.
L.F. Menezes, L.F. Onuchic
doaj
Dickkopf-3: Current Knowledge in Kidney Diseases
Frontiers in Physiology, 2020 Dickkopf-related protein 3 (DKK3) is a secreted glycoprotein that has been implicated in the pathogenesis of a variety of diseases. Recent evidence suggests that urinary DKK3 may serve as a potential biomarker for monitoring kidney disease progression ...
Xiangdong Fang +4 more
doaj +1 more source
Respiratory sympathetic modulation is augmented in chronic kidney disease [PDF]
Respiratory Physiology and Neurobiology, Elsevier, In press, 2019 Respiratory modulation of sympathetic nerve activity (respSNA) was studied in a hypertensive rodent model of chronic kidney disease (CKD) using Lewis Polycystic Kidney (LPK) rats and Lewis controls. In adult animals under in vivo anaesthetised conditions (n=8-10/strain), respiratory modulation of splanchnic and renal nerve activity was compared under ...
arxiv
TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis [PDF]
, 2020 Renal scarring after pyelonephritis is linked to long-term health risks for hypertension and chronic kidney disease. Androgen exposure increases susceptibility to, and severity of, uropathogenic Escherichia coli (UPEC) pyelonephritis and resultant ...
Collins, Christina A +5 more
core +1 more source
Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression. [PDF]
, 2015 BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder characterized by numerous fluid-filled cysts that frequently result in end-stage renal disease. While promising treatment options are in advanced clinical development,
Bernet, F. +11 more
core +2 more sources