Results 111 to 120 of about 451,989 (311)

Childhood Polycystic Kidney Disease

, 2015
Published
Cynthia Pan, Ellis D. Avner, William E. Sweeney, Ameya Patil   +3 more
openaire   +3 more sources

Polycystic Diseases in Visceral Organs

Obstetrics and Gynecology International, 2011
Primary cilia are nonmotile, microtubule-based, antenna-like organelles projecting from the apical surface of most mammalian cells. Elegant studies have established the importance of ciliary structure and function in signal transduction and the sensory ...
Shakila Abdul-Majeed, Surya M. Nauli
doaj   +1 more source

Splenectomy and Thymectomy in Human Renal Homotransplantation [PDF]

, 1963
Five patients with terminal renal failure have been treated with renal homografts. Total body irradiation and cytotoxic drugs were used to prevent rejection.
Marchioro, TL, Starzl, TE, Talmage, DW, Waddell, WR   +3 more
core   +1 more source

Health-related quality of life in patients with autosomal dominant polycystic kidney disease and CKD stages 1-4: a cross-sectional study.

American Journal of Kidney Diseases, 2014
BACKGROUND In people with early autosomal dominant polycystic kidney disease (ADPKD), average total kidney volume (TKV) is 3 times normal and increases by an average of 5% per year despite a seemingly normal glomerular filtration rate (GFR).
D. Miskulin, Kaleab Z. Abebe, Arlene Chapman, R. Perrone, Theodore I. Steinman, Vicente Torres, K. Bae, W. Braun, F. Winklhofer, M. Hogan, F. Rahbari-Oskoui, Charity G. Moore, M. Flessner, Robert W. Schrier   +13 more
semanticscholar   +1 more source

Mechanical Instabilities of Biological Tubes

, 2012
We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their division provokes a buckling instability.
A. P. Evan, Edouard Hannezo, F. K. Nelson, G. J. Beitel, Jacques Prost, Jean-François Joanny, L. W. Welling, Lord Rayleigh, P. F. J. New, S. Timoshenko   +9 more
core   +1 more source

New onset diabetes after kidney transplantation in patients with autosomal dominant polycystic kidney disease: systematic review protocol [PDF]

, 2015
Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder with numerous cysts developing in bilateral kidneys.
Ajabnoor, Barua, de Mattos, Guyatt, Harris, Hernández-Fisac, Kanaan, Kidney Disease: Improving Global Outcomes Transplant Work Group, Mao, McCarthy, Menon, Moher, Oetjen, Perrone, Pietrzak-Nowacka, Pietrzak-Nowacka, Pietrzak-Nowacka, Ruderman, Shamseer, Torra, Torres, Torres, Turkmen   +22 more
core   +1 more source

CRISPR-Cas9 system in autosomal dominant polycystic kidney disease: a comprehensive review [PDF]

Childhood Kidney Diseases
Genetic kidney diseases are caused by mutations in specific genes that significantly affect kidney development and function. Although the underlying pathogenic genes of many kidney diseases have been identified, an understanding of their mechanisms and ...
Seungyeon Kang, Se Jin Park, Min Ho Lee, Andreas Kronbichler, Jae Il Shin   +4 more
doaj   +1 more source

Prediction of Kidney Function from Biopsy Images Using Convolutional Neural Networks [PDF]

arXiv, 2017
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE study, a longitudinal cohort study whose goal is to set up infrastructure for observing the evolution of 3 forms of ...
arxiv  

Rationale and design of the DIPAK 1 study: a randomized controlled clinical trial assessing the efficacy of lanreotide to Halt disease progression in autosomal dominant polycystic kidney disease.

American Journal of Kidney Diseases, 2014
BACKGROUND There are limited therapeutic options to slow the progression of autosomal dominant polycystic kidney disease (ADPKD). Recent clinical studies indicate that somatostatin analogues are promising for treating polycystic liver disease and ...
E. Meijer, J. Drenth, Hedwig M. A. D’Agnolo, N. Casteleijn, J. D. de Fijter, T. Gevers, P. Kappert, D. Peters, M. Salih, D. Soonawala, E. M. Spithoven, V. Torres, F. W. Visser, J. Wetzels, R. Zietse, R. Gansevoort   +15 more
semanticscholar   +1 more source

Roles for Exosome in Various Kidney Diseases and Disorders

Frontiers in Pharmacology, 2020
Exosome is a nanoscale vesicle with a size range of 30–100 nm. It is secreted from cell to extracellular space by exocytosis after fusion of multivesicular body (MVB) (formed by endocytic vesicles) with plasma membrane.
Visith Thongboonkerd
doaj   +1 more source