Results 151 to 160 of about 54,094 (256)

How Pre‐Pregnancy Weight and Polycystic Ovary Syndrome Impact Pregnancy Outcomes: A Population‐Based Cohort Study

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Pre‐pregnancy overweight/obese status among women with polycystic ovary syndrome (PCOS) could increase the risk of at least one adverse pregnancy outcome (APO). This study aimed to determine how pre‐pregnancy weight and PCOS impact pregnancy outcomes. Methods For the current study, we used data collected in the Tehran Lipid
Elahe Sheklabadi, Marzieh Saei Ghare Naz, Maryam Mousavi, Maryam Rahmati, Seyed Alireza Ebadi, Fereidoun Azizi, Fahimeh Ramezani Tehrani   +6 more
wiley   +1 more source

Age- and height-adjusted total kidney volume growth rate in autosomal dominant polycystic kidney diseases. [PDF]

Clin Exp Nephrol, 2019
Higashihara E, Yamamoto K, Kaname S, Okegawa T, Tanbo M, Yamaguchi T, Shigemori K, Miyazaki I, Yokoyama K, Nutahara K.   +9 more
europepmc   +1 more source

Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications

Israel Journal of Chemistry, Volume 66, Issue 3, May 2026.
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff, Jemma Arakelyan, Billy Wai‐Lung Ng   +2 more
wiley   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang, Hui Jing, Yuhan Chen, Ling Zhong, Jiyun Yang   +4 more
wiley   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Polycystic kidney disease

Kidney International, 1982
openaire   +2 more sources

Autosomal Dominant Tubulointerstitial Kidney Disease Clinical Trial Simulator: Case Reports of Model‐Informed Drug Development

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) is the third most common inherited monogenic kidney disorder. Mutations in UMOD and MUC1 account for most cases, with the disease characterized by progressive eGFR decline leading to kidney failure. No disease‐modifying therapies exist, and transplantation is the only current option.
Shyam S. Ramesh, Mark Rogge, Jongjin Kim, Sanghoon Kang, Kendrah Kidd, Adrienne Williams, Julie Roignot, Katherine Blakeslee, Anthony J. Bleyer, Sarah Kim   +9 more
wiley   +1 more source

Presumptive Congenital Unilateral Renal Agenesis With Contralateral Dysplasia/Hypoplasia in a Golden Retriever

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
A 4‐year‐old Golden Retriever presented with polyuria, polydipsia and severe azotaemia, with multimodal imaging revealing complete presumptive left renal agenesis with a small dysplastic remnant and severe presumptive right renal dysplasia/hypoplasia with loss of normal corticomedullary architecture. To the authors’ knowledge, this represents the first
Hyewon Moon
wiley   +1 more source

Kidney Transplant Referral, Activation, and Transplantation Rates in a Single‐Center Cohort of Older Adults in Nova Scotia

Clinical Transplantation, Volume 40, Issue 5, May 2026.
ABSTRACT Introduction Kidney transplantation (KT) improves survival and quality of life for older adults with kidney failure, yet older adults may be referred less often. We aimed to compare KT referral, waitlist activation, and transplantation rates by age in a contemporary Canadian cohort.
Jacob B. Michaud, Karthik K. Tennankore, George L. Worthen, Bryce Kiberd, Amanda J. Vinson   +4 more
wiley   +1 more source

A novel frameshift variation of PKD1 in familial autosomal dominant polycystic kidney diseases: expanding the clinical phenotype and genetic spectrum of PKD1 disorders. [PDF]

BMC Med Genomics
Chen Q, Shi L, Zhu X.
europepmc   +1 more source