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Multicystic Kidney Disease in a Family With Tuberous Sclerosis Complex. [PDF]
Donald JS +4 more
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Advances and future perspectives of kidney organoid technology in renal disease research and clinical translation. [PDF]
Zhao Z +5 more
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Medical Management of Polycystic Liver Disease: A Position Statement From the European Reference Network on Hepatological Diseases. [PDF]
Heinrich S +16 more
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Evolution of Clinical Trial Design in ADPKD. [PDF]
Roth JR, Dahl NK, Garimella PS.
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Kynurenines in polycystic kidney disease
Journal of Nephrology, 2022Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder, characterized by kidney cyst formation. A major pathological feature of ADPKD is the development of interstitial inflammation.
Jost, Klawitter +8 more
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Comprehensive Physiology, 2017
ABSTRACT Renal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling. Hereditary polycystic kidney disease
Joseph, Ghata, Benjamin D, Cowley
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ABSTRACT Renal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling. Hereditary polycystic kidney disease
Joseph, Ghata, Benjamin D, Cowley
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Cilia and polycystic kidney disease
Seminars in Cell & Developmental Biology, 2021Polycystic kidney disease (PKD), comprising autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), is characterized by incessant cyst formation in the kidney and liver. ADPKD and ARPKD represent the leading genetic causes of renal disease in adults and children, respectively.
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Polycystic Kidney/Liver Disease
Clinics in Liver Disease, 2022Autosomal dominant polycystic kidney disease (ADPKD) is a genetic disorder that leads to chronic kidney disease and end-stage kidney disease (ESKD). Polycystic liver disease (PCLD) is the most common extrarenal manifestation of ADPKD. Though isolated PCLD and PCLD due to ADPKD are genetically distinct, they follow a similar clinical course of ...
Rebecca, Roediger +3 more
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