Results 161 to 170 of about 54,094 (256)

Identification of Urinary Exosomal microRNAs Associated With Subclinical Acute T‐Cell‐Mediated Rejection in Kidney Transplant Recipients

Clinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT This study aimed to evaluate the diagnostic utility of urinary exosomal microRNAs (miRNAs) in subclinical rejection following kidney transplantation by comparing miRNA expression profiles in urinary exosomes between patients with no evidence of rejection and patients with subclinical T‐cell‐mediated rejection (sc‐TCMR), as confirmed by ...
Soichiro Tajima, Miori Ono, Yuto Kawazoe, Hiroshi Noguchi, Tomohiro Shigematsu, Takashi Ogino, Shoji Nakamura, Takahiro Nakamura, Keizo Kaku, Takeshi Hirota, Ichiro Ieiri, Mayako Uchida   +11 more
wiley   +1 more source

A Snake Toxin Derivative for Treatment of Hyponatremia and Polycystic Kidney Diseases. [PDF]

J Am Soc Nephrol
Stanajic-Petrovic G, Keck M, Barbe P, Urman A, Correia E, Isnard P, Duong Van Huyen JP, Chmeis K, Diarra SS, Palea S, Theodoro F, Nguyen AL, Castelli F, Pruvost A, Zhao W, Mendre C, Mouillac B, Bienaimé F, Robin P, Kessler P, Llorens-Cortes C, Servent D, Nozach H, Maillère B, Guo D, Truillet C, Gilles N.   +26 more
europepmc   +1 more source

Real‐world treatment trajectories preceding GLP‐1 receptor agonist initiation in type 2 diabetes: A descriptive UK population‐based cohort study on adherence to national clinical guidelines

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3692-3702, May 2026.
Abstract Aims To investigate glucose‐lowering treatment trajectories preceding glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) initiation in UK primary care, while assessing alignment with contemporary UK clinical guidelines, considering calendar time, cardiovascular disease (CVD) history, and obesity status.
Franziska S. Ulrich, Morten Frost Nielsen, Nicola Napoli, Andrea M. Burden   +3 more
wiley   +1 more source

An extracellular vesicle based hypothesis for the genesis of the polycystic kidney diseases. [PDF]

Extracell Vesicle
Hogan MC, Ward CJ.
europepmc   +1 more source

Real‐world predictors of progression to type 2 diabetes among adults with prediabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3985-3996, May 2026.
Abstract Aims Assess predictors of progression to type 2 diabetes (T2D) among patients with prediabetes. Materials and methods This case–control study assessed adults with prediabetes using US claims and EMR‐linked data from January 1, 2016, through January 31, 2024.
Tyler Dunn, Riddhi Doshi, Victoria Divino, Justin Chen, Michael Radin, Dajun Tian, Lin Xie, Carolina Solis‐Herrera   +7 more
wiley   +1 more source

Healthcare Resource Utilisation and Cost of Obesity and Related Complications in the United States: A Systematic Literature Review

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4121-4136, May 2026.
ABSTRACT Aim Obesity is an increasingly prevalent, chronic, heterogeneous disease, associated with a variety of obesity‐related complications (ORCs). This systematic literature review assessed US healthcare resource utilisation (HCRU) and costs (direct and indirect) for people living with obesity (PwO) or overweight and ORCs.
Jaime P. Almandoz, Jamy D. Ard, Chellse Gazda, Shenelle Edwards‐Hampton   +3 more
wiley   +1 more source

Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In a rat model of DHEA/DHT‐induced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxin‐interacting protein (TXNIP) are potential causes of infertility in women with polycystic
Yajing Weng, Luxi Shangguan, Qi Shen, Zhengquan Zhu, Yaling Zhang, Jingwen Zhang, Guijun Yan, Shanmei Shen, Zou Xiang, Jianguo Ruan, Yanting Wen, Daojuan Wang, Yong Wang   +12 more
wiley   +1 more source

Vascular Endothelial Growth Factor C for Polycystic Kidney Diseases. [PDF]

J Am Soc Nephrol, 2016
Huang JL, Woolf AS, Kolatsi-Joannou M, Baluk P, Sandford RN, Peters DJ, McDonald DM, Price KL, Winyard PJ, Long DA.   +9 more
europepmc   +1 more source

Prenatal Diagnosis of Renal Cysts and Diabetes Syndrome (RCAD): A Case Report. [PDF]

Am J Case Rep
Manasar-Dyrbuś M, Stojko R, Paul-Samojedny M, Winkowska E, Staniczek J.   +4 more
europepmc   +1 more source

Emerging roles of ATP citrate lyase in kidney diseases: from pathogenic driver to therapeutic target. [PDF]

Ren Fail
Wei M, Tao M, Tan H, Jin Z, Yang Y, Xiao Z, Li G, Chen Y.   +7 more
europepmc   +1 more source