Results 161 to 170 of about 2,624,306 (259)

Upcoming therapies for steatotic liver disease: Translating breakthroughs into clinical practice

Journal of Internal Medicine, Volume 300, Issue 4, Page 440-460, October 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide and a leading cause of cirrhosis, hepatocellular carcinoma, and cardiometabolic morbidity. Often clinically silent until advanced fibrosis develops, management has largely relied on lifestyle interventions, with limited ...
Philip N. Newsome, Saima Ajaz
wiley   +1 more source

Contributions of the anion exchangers SLC26A1, SLC26A2, SLC26A3, and SLC26A6 to intestinal oxalate transport in human Caco2‐BBE cells

Physiological Reports, Volume 14, Issue 19, October 2026.
Abstract Kidney stones affect ~1 in 5 men and 1 in 11 women, with 70%–80% being composed of calcium oxalate. Knowing the contributions of anion exchangers SLC26A2 (A2), A3, and A6 to apical and A1 to basolateral oxalate transport in human intestinal Caco2‐BBE (C2) cells is important since enhancing intestinal oxalate secretion (A6/2/?A1) and reducing ...
Khalid A. Abdelhalim, Donna Arvans, Yanzhe Wang, Mohamed Elfatih H. Bashir, Hatim A. Hassan   +4 more
wiley   +1 more source

Cobamide Scavenging and Import via a Multiprotein Extracellular Relay in Bacteroides thetaiotaomicron

ChemBioChem, Volume 27, Issue 18, 28 September 2026.
Bacteroides thetaiotaomicron competes with gut microbes and the host for a limited cobamide pool. To meet this demand, it deploys surface associated lipoproteins (BtuJ, BtuH, BtuK, BtuG), three BtuB paralogs, and extracellular vesicles that extend cobamide capture beyond the cell surface. This review examines the structural and mechanistic evidence for
Alexander Drake, Romila Mascarenhas
wiley   +1 more source

A novel frameshift variation of PKD1 in familial autosomal dominant polycystic kidney diseases: expanding the clinical phenotype and genetic spectrum of PKD1 disorders. [PDF]

BMC Med Genomics
Chen Q, Shi L, Zhu X.
europepmc   +1 more source

Polycystic kidney disease

Kidney International, 1982
openaire   +2 more sources

Kidney: Polycystic Liver (Microscopic) Type I Polycystic Kidney

, 1900
Polycystic Liver (Microscopic) Type I Polycystic Kidney (3 sections: top-liver, bottom L, R ...
MUSC Department of Pathology and Laboratory Medicine
core  

A Snake Toxin Derivative for Treatment of Hyponatremia and Polycystic Kidney Diseases. [PDF]

J Am Soc Nephrol
Stanajic-Petrovic G, Keck M, Barbe P, Urman A, Correia E, Isnard P, Duong Van Huyen JP, Chmeis K, Diarra SS, Palea S, Theodoro F, Nguyen AL, Castelli F, Pruvost A, Zhao W, Mendre C, Mouillac B, Bienaimé F, Robin P, Kessler P, Llorens-Cortes C, Servent D, Nozach H, Maillère B, Guo D, Truillet C, Gilles N.   +26 more
europepmc   +1 more source

An extracellular vesicle based hypothesis for the genesis of the polycystic kidney diseases. [PDF]

Extracell Vesicle
Hogan MC, Ward CJ.
europepmc   +1 more source

Evidence for a tubular basement membrane-cilia connection in autosomal dominant polycystic kidney disease pathogenesis. [PDF]

J Clin Invest
Sussman CR, Harris PC.
europepmc   +1 more source

The population frequency of predicted pathogenic variants in the genes associated with Autosomal Dominant Polycystic Liver Disease (ADPLD) and kidney cysts. [PDF]

PLoS One
Varughese S, Huang M, Savige J.
europepmc   +1 more source