Results 81 to 90 of about 451,989 (311)
The Kidneys Are Not All Normal: Investigating the Speckle Distributions of Transplanted Kidneys [PDF]
arXiv, 2022 Modelling ultrasound speckle has generated considerable interest for its ability to characterize tissue properties. As speckle is dependent on the underlying tissue architecture, modelling it may aid in tasks like segmentation or disease detection. However, for the transplanted kidney where ultrasound is commonly used to investigate dysfunction, it is ...
arxiv
American Society of Nephrology. Clinical Journal, 2010 Mammalian target of rapamycin (mTOR) is the core component of two complexes, mTORC1 and mTORC2. mTORC1 is inhibited by rapamycin and analogues. mTORC2 is impeded only in some cell types by prolonged exposure to these compounds.
V. Torres +8 more
semanticscholar +1 more source
Research directions for kidney stone disease [PDF]
arXiv, 2023 Kidney stone disease poses a major burden to patients and healthcare systems around the world. The formation of kidney stones may occur over months or years, but many patients are diagnosed at a late stage, suffer excruciating pain, and require surgical intervention to physically remove the stones.
arxiv
MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Journal of the American Society of Nephrology, 2016 Autosomal dominant polycystic kidney disease (ADPKD), one of the most common monogenetic disorders, is characterized by kidney failure caused by bilateral renal cyst growth.
R. Lakhia +9 more
semanticscholar +1 more source
Structural and molecular basis of the assembly of the TRPP2/PKD1 complex [PDF]
, 2009 Mutations in PKD1 and TRPP2 account for nearly all cases of autosomal dominant polycystic kidney disease (ADPKD). These 2 proteins form a receptor/ion channel complex on the cell surface. Using a combination of biochemistry, crystallography, and a single-
Buraei, Z. +8 more
core +3 more sources
Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]
arXiv, 2023 While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv
Microvesicles and exosomes: new players in metabolic and cardiovascular disease [PDF]
, 2016 The past decade has witnessed an exponential increase in the number of publications referring to extracellular vesicles (EVs). For many years considered to be extracellular debris, EVs are now seen as novel mediators of endocrine signalling via cell-to ...
Charlotte Lawson +21 more
core +2 more sources
Renal cell carcinoma in autosomal dominant polycystic kidney disease: A case report
Radiology Case Reports, 2023 Autosomal dominant polycystic kidney disease (ADPKD) is one of the congenital cystic renal diseases with the highest incidence. ADPKD was suspected of being a risk factor for the emergence of RCC.
Gullyawan Rooseno +3 more
doaj
Saudi Journal of Medicine and Medical Sciences, 2016 Multiple liver cysts can be an isolated disease (isolated polycystic liver disease [PLD]) or they can be part of multi-organ involvement in other diseases, such as adult autosomal dominant polycystic disease (APD), which is the most frequently inherited ...
Adil H Al-Harthi +2 more
doaj +1 more source
Cystic kidney diseases: many ways to form a cyst [PDF]
, 2012 Renal cysts are a common radiological finding in both adults and children. They occur in a variety of conditions, and the clinical presentation, management, and prognosis varies widely.
Loftus, H., Ong, A.C.M.
core +1 more source