Regeneration in Aesthetic Medicine: Mechanisms, Evidence, and Clinical Boundaries. [PDF]
J Cosmet DermatolABSTRACT Background Regeneration has emerged as a key concept in aesthetic medicine as the field evolves from predominantly volumetric correction toward biologically oriented strategies aimed at improving tissue quality, function, and long‐term structural integrity.
Barbosa AP.
europepmc +2 more sources
Prospective Observational Study of Polynucleotide Injections for Periorbital Rhytides. [PDF]
J Cosmet DermatolABSTRACT Introduction Polynucleotides (PN), derived from salmon sperm DNA, are highly purified DNA fragments with reported tissue‐repair and anti‐inflammatory properties mediated through adenosine A2A receptor activation. These agents have been increasingly used in aesthetic dermatology for skin rejuvenation and scar treatment.
Ziade G +6 more
europepmc +2 more sources
The Effect of Polydeoxyribonucleotide on Chronic Non-healing Wound of an Amputee: A Case Report [PDF]
Annals of Rehabilitation Medicine, 2018 Polydeoxyribonucleotide (PDRN) is safe and effective in wound healing, cellular growth, synthesis of extracellular matrix protein, and inflammation reduction via activation of adenosine A2 receptors. We report a 28-year-old male patient treated with PDRN
Junho Shin +3 more
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AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Polydeoxyribonucleotide-delivering therapeutic hydrogel for diabetic wound healing [PDF]
Scientific Reports, 2020 AbstractPatients with diabetes experience delayed wound healing because of the uncontrolled glucose level in their bloodstream, which leads to impaired function of white blood cells, poor circulation, decreased production and repair of new blood vessels.
Da Yong Shin +5 more
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Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Polydeoxyribonucleotide in the Treatment of Knee Osteoarthritis [PDF]
Annals of Rehabilitation Medicine, 2019 Objective To assess the clinical efficacy and safety of intra-articular injection of hyaluronic acid (HA) combined with polydeoxyribonucleotide (PDRN) in patients with knee osteoarthritis in comparison with that of HA alone.
Seihee Yoon +4 more
doaj +1 more source
Archives of Plastic Surgery, 2017 Background Polydeoxyribonucleotide (PDRN) is known to have anti-inflammatory and angiogenic effects and to accelerate wound healing. The aim of this study was to investigate whether PDRN could improve peripheral tissue oxygenation and angiogenesis in ...
Seoyoung Kim +4 more
doaj +1 more source
Design, synthesis and antibacterial activity of minor groove binders: the role of non-cationic tail groups [PDF]
, 2012 he design and synthesis of a new class of minor groove binder (MGBs) in which, the cationic tail group has been replaced by a neutral, polar variant including cyanoguanidine, nitroalkene, and trifluoroacetamide groups.
Bourdin, Claire +9 more
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Polydeoxyribonucleotide: A promising skin anti-aging agent
Chinese Journal of Plastic and Reconstructive Surgery, 2022 Polydeoxyribonucleotide (PDRN) consists of DNA fragments with molecular weights ranging from 50 to 1 500 kDa, which are mainly extracted from the sperm cells of salmon trout or chum salmon. Many preclinical and clinical studies have demonstrated the properties of PDRN.
Aawrish Khan +6 more
openaire +2 more sources
Changes in microRNA expression profiles in HIV-1-transfected human cells [PDF]
, 2005 MicroRNAs (miRNAs) are small RNAs of 18–25 nucleotides (nt) in length that play important roles in regulating a variety of biological processes. Recent studies suggest that cellular miRNAs may serve to control the replication of viruses in cells. If such
Benkirane Monsef +5 more
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