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Xanthones from Polygala tenuifolia
Abstract From the roots of Polygala tenuifolia , six new xanthones, 3-hydroxy-2,8-dimethoxyxanthone, 7-hydroxy-1,2,3-trimethoxyxanthone, 3-hydroxy-1,2,7-trimethoxyxanthone, 1,7-dimethoxy-2,3-methylenedioxyxanthone, 6,8-dihydroxy-1,2,4-trimethoxyxanthone, and 6,8-dihydroxy-1,2,3-trimethoxyxanthone, have been isolated along with seven known xanthones,
Tetsuro Fujita +3 more
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Yuanzhi, Radix Polygalae, is the dry root of Polygala tenuifolia Willd. or P. sibirica L. (Polygalaceae) collected in the spring and fall. It is officially listed in the Chinese Pharmacopoeia and is used in traditional Chinese medicine as a mucolytic for the treatment of cough. It is further used as a sedative and for antiswelling purposes. Two galenic
Weici Tang, Gerhard Eisenbrand
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Polygala Sibirica and Polygala Tenuifolia
G. M. Hocking
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The Interaction Between Two Metabolites of Polygala tenuifolia and Cholinesterases
Protein & Peptide Letters, 2022Objective: The work aimed to compare the binding between the two main components of Polygala tenuifolia Willd. and two cholinesterases (ChEs) by using a variety of spectral techniques. Methods: Two main components of Polygala tenuifolia Willd. included Tenuifolin (Ten) and Onjisaponin B (Onj B), and two ChEs included acetylcholinesterase (AChE) and ...
Chengxia, Gao, Huizhi, Du
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A new glycoside from Polygala tenuifolia Willd
Chinese Chemical Letters, 2008Abstract A new triterpenoid glycoside, 3-β- O -β- d -glucopyranosyl presenegenin 28- O -α- l -arabipyranosyl(1 → 3)-β- d -xylopyranosyl(1 → 4)-[β- d -apiofuranosyl(1 → 3)]-α- l -rhamnopyranosyl(1 → 2)-[α- l -rhamnopyranosyl(1 → 3)]-β- d -fucopyranosyl ester (1) was isolated from the Polygala tenuifolia Willd., together with two known saponins ...
Tun Hai Xu +8 more
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Structural elucidation and anti-neuroinflammatory activity of Polygala tenuifolia polysaccharide
International Journal of Biological Macromolecules, 2022Polygala tenuifolia is extensively used to treat amnesia in traditional Chinese medicine, and pharmacological studies have reported the beneficial effects of P. tenuifolia on intelligence and cognition. In the present study, the crude polysaccharide alkali-extracted from P. tenuifolia roots (PTB) inhibited lipopolysaccharide-induced microglia/astrocyte
Zhiwei, Zeng +7 more
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Two xanthones from Polygala tenuifolia
Phytochemistry, 1991Abstract Two new xanthones, onjixanthones I and II, and four known xanthones, 1,6-dihydroxy-3,7-dimethoxyxanthone, 1,7-dihydroxy-3-methoxyxanthone, 1,6-dihydroxy-3,5,7-trimethoxyxanthone and 1-hydroxy-3,6,7-trimethoxyxanthone were isolated from roots of Polygala tenuifolia.
Yukinobu Ikeya +3 more
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Antidepressant Principles of the Roots of Polygala tenuifolia
Journal of Natural Products, 2006[(125)I]RTI-55-membrane binding assay-guided fractionation and separation of a water-soluble extract of the roots of Polygala tenuifolia gave five new oligosaccharide derivatives, polygalatenosides A-E (1-5). The structures of these new oligosaccharides were established on the basis of spectroscopic evidence.
Mo-Chi, Cheng +5 more
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Genotoxicity studies on the root extract of Polygala tenuifolia Willdenow
Regulatory Toxicology and Pharmacology, 2015The root of Polygala tenuifolia Willdenow has been used for the treatment against insomnia, amnesia, depression, palpitations with anxiety, and memory improvement. However, there is no sufficient background information on toxicological evaluation of the root to given an assurance of safety for developing dietary supplements and functional foods.
Ki Young Shin +4 more
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[Chemical constituents of Polygala tenuifolia root].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2015To study the chemical constituents from the root of Polygala tenuifolia.Silica gel,Sephadex LH-20 and ODS chromatographic techniques were used to study the chemical constituents of Polygala tenuifolia, and the chemical structures were elucidated by application of spectral data.Eight-compounds were obtained and their structure were identified as 7 ...
Liang-liang, Xu +4 more
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