Attenuating Effect of Polygala tenuifolia Willd. Seed Oil on Progression of MAFLD [PDF]
Frontiers in Pharmacology, 2023 Introduction: Metabolic-associated fatty liver disease (MAFLD) is a common chronic metabolic disease that seriously threatens human health. The pharmacological activity of unsaturated fatty acid-rich vegetable oil interventions in the treatment of MAFLD ...
Shufei Liang, Tianqi Cai, Xinhua Song
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Predicting the Potential Distribution of Polygala tenuifolia Willd. under Climate Change in China. [PDF]
PLoS ONE, 2016 Global warming has created opportunities and challenges for the survival and development of species. Determining how climate change may impact multiple ecosystem levels and lead to various species adaptations is necessary for both biodiversity ...
Hongjun Jiang +5 more
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Polygala tenuifolia Willd. Extract Delays Non-Alcoholic Fatty Liver Disease Progression in Rats via the COX2 and PERK-elF2α-ATF4 Pathway [PDF]
Frontiers in PharmacologyBackgroundNon-alcoholic fatty liver disease (NAFLD), a chronic liver disease posing a severe threat to human health, currently lacks specific therapeutic drugs. Our previous studies have demonstrated that Polygala tenuifolia Willd.
Yanju Liu, Zhongshi Zhou
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Integrative Network Pharmacology, Transcriptomics, and Microbiomics Elucidate the Therapeutic Mechanism of Polygala tenuifolia Willd Water Extract in Chronic Obstructive Pulmonary Disease [PDF]
Frontiers in MicrobiologyBackgroundPolygala tenuifolia Willd (PT) is a plant with both medicinal and edible values. Traditionally, it has been used for sedation, enhancing cognition, resolving phlegm, and relieving cough.
Hongqiang Lin, Yiming An
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Sequence characteristics, expression and subcellular localization of PtCYP721A57 gene from cytochrome P450 family in Polygala tenuifolia willd [PDF]
PeerJThe Cytochrome P450 (CYP450) family is the largest enzyme protein family in plants, distributed across various organs and involved in significant catalytic activities in primary and secondary metabolic processes.
Yao Luo +7 more
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The Complete Chloroplast Genome of Polygala tenuifolia, a Critically Endangered Species in Korea
Mitochondrial DNA Part B: Resources, 2020 Polygala tenuifolia Willd. is an Oriental plant that is widely distributed in East Asia; but the medicinal plant is a critically endangered species in Korea, where only a few individuals exist.
Won-Bum Cho, Dong-Hyuk Lee
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Transcriptome-based identification of the WRKY gene family in Polygala tenuifolia Willd. and their response to cold stress [PDF]
BMC Plant BiologyBackground Polygala tenuifolia Willd. is an important traditional medicinal plant widely used in prescriptions for cognitive enhancement. Cold stress severely affects seedling growth and medicinal quality in P.
Jing Liu +6 more
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HMGR and CHS gene cloning, characterizations and tissue-specific expressions in Polygala tenuifolia Willd. [PDF]
PLoS ONETriterpenoid saponins and flavonoids have several pharmacological activities against P. tenuifolia. The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) and chalcone synthase (CHS) are the rate-limiting enzymes of triterpenoid saponin and flavonoid ...
Yang Liu +8 more
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Frontiers in Pharmacology, 2022 Senegenin is the main bioactive ingredient isolated from the dried roots of Polygala tenuifolia Willd. In recent years, senegenin has been proved to possess a variety of pharmacological activities, such as anti-oxidation, anti-inflammation, anti ...
Xijun Wang
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Genome-wide identification and expression profiling of the ERF subfamily in Polygala tenuifolia seedlings under drought stress [PDF]
BMC Plant BiologyBackground Polygala tenuifolia Willd. (P. tenuifolia) is one of the source plants of the traditional Chinese medicine ‘Yuanzhi’ and is widely used in clinical practice.
Yujiao Sun +9 more
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