Results 21 to 30 of about 27,060 (161)

Polygalae Radix: review of metabolites, pharmacological activities and toxicology [PDF]

Frontiers in Pharmacology
Polygalae Radix: is the dried root of Polygala tenuifolia Willd. or Polygala sibirica L., which has the effect of improving memory and cognitive function in traditional Chinese medicine.
Meihua Liu, Xin Wang, Dejiang Gao
doaj   +2 more sources

Combination of tenuigenin-based Polygala tenuifolia willd. root extract and forsythoside a improved Alzheimer’s disease

Natural Product Research
Tenuigenin is a kind of the main active ingredients in roots of Polygala tenuifolia Willd. (a species in the genus Polygala, family Polygalaceae) and forsythoside A (FA) is one of the main active ingredients of Forsythia suspensa (Thunb.) Vahl. (a species in the genus Forsythia, family Meliaceae).
Guocui, Liang, Chengxia, Gao, Liwei, Zhang, Huizhi, Du   +3 more
openaire   +3 more sources

The efficacy and safety of Chinese herbal medicine for mild cognitive impairment: a systematic review and meta-analysis of randomized placebo-controlled trials [PDF]

Frontiers in Pharmacology
Objective: Effective and safe treatments for mild cognitive impairment (MCI) are limited. Chinese herbal medicine (CHM) is commonly used in China to manage MCI. However, its efficacy and safety remain uncertain.
Lingling Liu, Lingling Liu, Claire Shuiqing Zhang, Anthony Lin Zhang, Yefeng Cai, Charlie Changli Xue, Charlie Changli Xue   +6 more
doaj   +2 more sources

Magnolia Officinalis Alcohol Extract Alleviates the Intestinal Injury Induced by Polygala Tenuifolia Through Regulating the PI3K/AKT/NF-κB Signaling Pathway and Intestinal Flora [PDF]

Drug Design, Development and Therapy
Si Liu, Dan Yang, Wen Li, Qiuping Chen, Danni Lu, Liang Xiong, Junjie Wu, Hui Ao, Lihua Huang State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, People’
Liu S, Yang D, Li W, Chen Q, Lu D, Xiong L, Wu J, Ao H, Huang L   +8 more
doaj   +1 more source

Tenuifoliside Z1, an undescribed glycolipid from Polygala tenuifolia Willd. roots with antioxidant activity

Records of Natural Products
Abstract: a new glycolipid, tenuifoliside Z1 (1), together with four known glycolipid compounds (2-5) has been isolated from the root of Polygala tenuifolia Willd. Their structures were determined through spectroscopic analysis, chemical derivatization, and comparison with spectroscopic data reported in the literature.
Yu-chen Zhou, Yong-Jiang Wang, Da-Le Guo, Mei-Hong Liu, Mei-Hong Liu   +4 more
openaire   +2 more sources

Neuroprotective effects of the aerial parts of Polygala tenuifolia Willd extract on scopolamine-induced learning and memory impairments in mice. [PDF]

Biomed Rep, 2020
Alzheimer's disease is a common neurodegenerative disease characterized by progressive cognitive dysfunction and behavioral impairment. Aerial parts of Polygala tenuifolia Willd (APT) is a traditional Chinese medicine used for the treatment of amnesia. The present study aimed to investigate the protective effects of APT on scopolamine-induced learning ...
Wang X, Zhang D, Song W, Cai CF, Zhou Z, Fu Q, Yan X, Cao Y, Fang M.   +8 more
europepmc   +4 more sources

Protective Effects and Mechanism of Radix Polygalae Against Neurological Diseases as Well as Effective Substance

Frontiers in Psychiatry, 2021
Radix Polygalae (also known as Yuanzhi in China) is the dried rhizome of Polygala tenuifolia Willd. or Polygala sibirica L., which is a famous Chinese herb and has been widely used for centuries in traditional medicines including expectorants, tonics ...
Ning Jiang, Ning Jiang, Shanshan Wei, Yiwen Zhang, Wenlu He, Haiyue Pei, Hong Huang, Qiong Wang, Qiong Wang, Xinmin Liu, Xinmin Liu   +10 more
doaj   +1 more source

Traditional Chinese medicine: saponins, critical micellar concentrations and partition coefficients

Phytochemical Analysis, Volume 34, Issue 4, Page 414-420, June 2023., 2023
Abstract Introduction Traditional Chinese medicine (TCM) revolves around complex mixtures bound to specific roles within the formulation, among which saponin‐containing plants with alleged properties of harmonising or detoxifying other compounds present in the preparations.
Cédric Barthel, Georges Massiot, Catherine Lavaud   +2 more
wiley   +1 more source

Structural Characterization and Immunomodulatory Activity of Polysaccharides from Polygonatum sibiricum Prepared with Deep Eutectic Solvents

Journal of Food Quality, Volume 2023, Issue 1, 2023., 2023
Deep eutectic solvents (DES), as a new, efficient, and green solvents, have attracted more attention in recent years. This study was performed to extract Polygonatum sibiricum polysaccharides using DES (DPSP). Subsequently, DPSP was subjected to DEAE‐Sepharose Fast Flow and Sephadex G‐100 column for further purification (DPSP‐3).
Jikun Meng, Chunbo Guan, Qiufeng Chen, Xiao Pang, Heqin Wang, Xinwen Cui, Ran Ye, Xiuqing Zhang, Seyed Mohammad Taghi Gharibzahedi   +8 more
wiley   +1 more source

Polygala tenuifolia: a source for anti-Alzheimer’s disease drugs

Pharmaceutical Biology, 2020
Context Alzheimer’s disease (AD) is a chronic neurodegenerative disease that originates from central nervous system lesions or recessions. Current estimates suggest that this disease affects over 35 million people worldwide.
Xinxin Deng, Shipeng Zhao, Xinqi Liu, Lu Han, Ruizhou Wang, Huifeng Hao, Yanna Jiao, Shuyan Han, Changcai Bai   +8 more
doaj   +1 more source