Results 31 to 40 of about 27,060 (161)

Gastrodia elata BI.:A Comprehensive Review of Its Traditional Use, Botany, Phytochemistry, Pharmacology, and Pharmacokinetics

Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Ethnopharmacological Relevance. The medicinal use of Gastrodia elata BI., a dry tuber of the orchid family, has a long history. Gastrodia elata BI. has the functions of calming the liver, relieving muscle spasms, and dispelling gas. Aim of this Review.
Ya-Nan Wu, Si-Hua Wen, Wei Zhang, Shang-Shang Yu, Kai Yang, Ding Liu, Chong-Bo Zhao, Jing Sun, Li Hua   +8 more
wiley   +1 more source

Jia‐Wei‐Kai‐Xin‐San Treatment Alleviated Mild Cognitive Impairment through Anti‐Inflammatory and Antiapoptotic Mechanisms in SAMP8 Mice

Mediators of Inflammation, Volume 2023, Issue 1, 2023., 2023
Background. Alleviating mild cognitive impairment (MCI) is crucial to delay the progression of Alzheimer’s disease (AD). Jia‐Wei‐Kai‐Xin‐San (JWKXS) is applied for treating AD with MCI. However, the mechanism of JWKXS in the treatment of MCI is unclear. Thus, this study aimed to investigate the effect and mechanism of JWKXS in SAMP8 mice models of MCI.
Xiaolu Zhang, Yingxin Sun, Qun Yu, Wenyun Zeng, Yue Zhang, Miao Zeng, Kexin Pang, Yifei Yu, Jiali Gan, Huhu Li, Lin Yang, Xijuan Jiang, Sachchida Nand Rai   +12 more
wiley   +1 more source

Xanthones and Xanthone O‐β‐D‐Glucosides from the Roots of Polygala azizsancarii Dönmez

Chemistry &Biodiversity, Volume 19, Issue 8, August 2022., 2022
Abstract Nine xanthone derivatives (1–9) were isolated from the roots of Polygala azizsancarii, which is a narrow endemic species for the flora of Türkiye. Based on all of the evidence, the structures of 1–9 were established as two previously undescribed xanthone O‐glucosides, 3‐O‐β‐D‐glucopyranosyloxy‐1,6‐dihydroxy‐2,5,7‐trimethoxyxanthone (1), 3‐O‐β ...
İhsan Çalış, Ayşe Ünlü, Zübeyde Uğurlu Aydın, Ali A. Dönmez, Hasan Soliman Yusufoğlu, Simon Jurt, Anthony Linden   +6 more
wiley   +1 more source

Chinese medicine in the treatment of autoimmune hepatitis: Progress and future opportunities

Animal Models and Experimental Medicine, Volume 5, Issue 2, Page 95-107, April 2022., 2022
Generalized relations between traditional Chinese medicines and different animal models for AIH. Abstract Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease occurring in individuals of all ages with a higher incidence in females and characterized by hypergammaglobulinemia, elevated serum autoantibodies and histological features of ...
Jia Liu, Zhi Ma, Han Li, Xiaojiaoyang Li
wiley   +1 more source

3,6'‐disinapoyl sucrose attenuates Aβ1‐42‐ induced neurotoxicity in Caenorhabditis elegans by enhancing antioxidation and regulating autophagy

Journal of Cellular and Molecular Medicine, Volume 26, Issue 4, Page 1024-1033, February 2022., 2022
Abstract The aggregation of β‐amyloid (Aβ) has the neurotoxicity, which is thought to play critical role in the pathogenesis of Alzheimer's disease (AD). Inhibiting Aβ deposition and neurotoxicity has been considered as an important strategy for AD treatment.
Xiaoli Tang, Yuming Zhao, Yanan Liu, Yang Liu, Yue Liu, Fenxi Niu, Fang Fang   +6 more
wiley   +1 more source

Active Compounds and Targets of Yuanzhi Powder in Treating Alzheimer’s Disease and Its Relationship with Immune Infiltration Based on HPLC Fingerprint and Network Pharmacology

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Background. Yuanzhi powder (YZP) has been extensively investigated as a natural prescription with therapeutic benefits for Alzheimer’s disease (AD). However, its active compounds and underlying immune mechanism for treating AD are still unclear. This study aimed to investigate the immune mechanism of YZP against AD through high‐performance liquid ...
Qingsong Liu, Shaofeng Wang, Yanwei Hao, Jiaxin Li, Wei Li, Yi Zhang, Bin Li, Samuel Martins Silvestre   +7 more
wiley   +1 more source

Herb pair of Polygala tenuifolia Willd and Acorus tatarinowii Schott decoction attenuates seizures and alleviates anxiety in mice:

Pakistan Journal of Pharmaceutical Sciences, 2023
Currently, prolong use of standard anti-epileptics may cause tolerance and ineffective for about 30% of epileptic patients. Medicinal plants provide an attractive therapeutic effect in preventing and treating seizures in traditional and folk medicine. In
Evidence for modulating inflammation, alleviating oxidative stress, mediating GABA pathway Yulu Xie, Yan Yang, Xufang Yuan, Ying Liu, Xirui He   +6 more
doaj   +1 more source

GC/MS‐Based Urine Metabolomics Study on the Ameliorative Effect of Xanthoceras sorbifolia Extract on Alzheimer’s Disease in Mice

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
The cause of Alzheimer’s disease, the most common type of dementia today, is still unclear, and in current research, there are no drugs that work relatively well. Therefore, the study for new drugs to treat Alzheimer’s disease is an urgent research need. Research on the improvement of Alzheimer’s disease with extracts of Xanthoceras sorbifolia has been
Rui Han, Min Wang, Li Wang, Yichen Zhang, Xin Li, Yijun Hou, Jing Yan, Xiaojing Pan, M. Maulidiani   +8 more
wiley   +1 more source

Kai‐Xin‐San Protects Depression Mice Against CORT‐Induced Neuronal Injury by Inhibiting Microglia Activation and Oxidative Stress

Evidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Objective. Traditional Chinese medicine formula Kai‐Xin‐San (KXS) is used to treat psychiatric disorders, especially in anxiety and depression. However, the precise molecular mechanism of action remains unclear. In this study, we investigated the antidepressant effect of KXS on inhibiting inflammation and oxidative stress in corticosterone (CORT ...
Guiqin Bai, Shangwen Jing, Huimin Cao, Yiqi Qiao, Gongchan Chen, Lining Duan, Yuna Yang, Min Li, Weirong Li, Xiang Chang, Cong Yang, Qi Wang, Guoqi Zhu   +12 more
wiley   +1 more source

Inhibitory Effect of the root of Polygala tenuifolia on Bradykinin and COX 2-Mediated Pain and Inflammatory Activity [PDF]

, 2013
Purpose: To gain insight into the mechanisms of analgesic and anti-inflammatory activities of the root extract of Polygala tenuifolia . Methods: Polygala tenuifolia was extracted with 70 % methanol and tested for analgesic and anti-inflammatory ...
Oh, Jung Jin, Kim, Sung-Jin
core   +4 more sources