Two Cycloartenol Synthases for Phytosterol Biosynthesis in Polygala tenuifolia Willd [PDF]
International Journal of Molecular Sciences, 2017 Oxidosqualene cyclases (OSCs) are enzymes that play a key role in control of the biosynthesis of phytosterols and triterpene saponins. In order to uncover OSC genes from Polygala tenuifolia seedlings induced by methyl jasmonate (MeJA), RNA-sequencing analysis was performed using the Illumina sequencing platform.
Ok Tae Kim, Woo Moon Lee
exaly +6 more sources
Saponin components in Polygala tenuifolia as potential candidate drugs for treating dementia [PDF]
Frontiers in PharmacologyObjectiveThis study aims to elucidate the intervention effects of saponin components from Polygala tenuifolia Willd (Polygalaceae) on dementia, providing experimental evidence and new insights for the research and application of saponins in the field of ...
Songzhe Li +5 more
doaj +4 more sources
Effects of the Crude Extract of Polygala tenuifolia Willd on Human Sperm in Vitro [PDF]
Journal of Zhejiang University: Science B, 2011 The aim of the present study is to analyze sperm membrane changes and the spermicidal effect in treatment with the crude extract from Polygala tenuifolia Willd (PTW) in vitro. The root of PTW was extracted in distilled water. Normal human spermatozoa were used to assess the spermicidal activity (Sander-Cramer assay) of the extract from the PTW root ...
Mei-Hua Zhang, Yi Qiu
exaly +5 more sources
Chemical Constituents of the Roots of Polygala tenuifolia and Their Anti-Inflammatory Effects
Plants, 2022 Increasing scientific evidence has demonstrated that the roots of Polygala tenuifolia Willd. have pharmacological effects related to anti-inflammation. Therefore, the aim of this study is to investigate the chemical constituents from P.
So-Ri Son +5 more
doaj +2 more sources
Integrated Gut Microbiota-Drug Interaction Analysis and Network Pharmacology for the Investigation of Renal-Protective Effect of <i>Polygala tenuifolia</i> Willd. [PDF]
Int J Mol SciPolygala tenuifolia Willd., a widely used traditional Chinese medicine, has the function of coordinating heart and kidney and eliminating swelling. However, its renal-protective efficacy and possible material basis remain unknown. The aim of the study was to investigate the renal-protective effect of Polygala tenuifolia Willd.
Hu JC +12 more
europepmc +4 more sources
Avicularin and Senegenin Suppress TRPV3-Associated TSLP Expression in Human Keratinocytes [PDF]
CellsTransient receptor potential vanilloid channel 3 (TRPV3) is a keratinocyte-expressed ion channel that regulates calcium signaling and thymic stromal lymphopoietin (TSLP) production, contributing to pruritic inflammatory skin diseases. Although avicularin
Han Bi Kim +5 more
doaj +2 more sources
Journal of Pharmacy and Pharmacology, 2011 Abstract Objective The present study was designed to observe the effects of 3,6′-disinapoyl sucrose (DISS), an active oligosaccharide ester component obtained from the roots of Polygala tenuifolia Willd., on behavioral and biochemical aspects of depression induced by chronic mild stress (CMS ...
Yuan, Hu +5 more
openaire +3 more sources
A review of the botany, metabolites, pharmacology, toxicity, industrial applications, and processing of Polygalae Radix: the “key medicine for nourishing life” [PDF]
Frontiers in PharmacologyPolygalae radix (PR) is the dried root of Polygala tenuifolia Willd. and Polygala sibirica L. and enjoys the reputation as the “key medicine for nourishing life.” In this study, information about “Polygala tenuifolia Willd.,” “Polygala sibirica L.,” and “
Hongtuo Kuang +4 more
doaj +2 more sources
Extract of Polygala tenuifolia, Angelica tenuissima, and Dimocarpus longan improve skin wound healing in streptozotocin- induced diabetic mouse [PDF]
Frontiers in PharmacologyObjectiveChronic skin wounds caused by diabetes, peripheral artery disease, pressure ulcers, and venous insufficiency do not fully recover anatomically and functionally.
Hayan Jeong +9 more
doaj +2 more sources
Polygala oligosaccharide esters improve memory disorder by restoring gut microbiota homeostasis through the regulation of the “gut-brain” axis [PDF]
Chinese MedicineBackground Yuanzhi (Polygala tenuifolia Willd.) possesses the effects of calming the spirit, enhancing intelligence, regulating the heart-kidney connection, eliminating phlegm, and reducing swelling.
Yan Wang +9 more
doaj +2 more sources