Results 41 to 50 of about 27,060 (161)

Effect of topical application of two Polygala tenuifolia species decoction on guinea pig skin [PDF]

, 2017
Purpose: To investigate the effect of the topical decoction of Polygala tenuifolia Willd. and Polygala sibirica L. on a guinea pig model of sore and ulcer.Method: A guinea pig model of sore and ulcer was produced by Staphylococcus aureus, and 80 guinea ...
Shi, Jingjing, Bai, Ming, Miao, Mingsan, Wang, Tan, Guo, Lin, Xin, Weiyun   +5 more
core   +1 more source

Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway

Frontiers in Pharmacology, 2022
Background: Alzheimer’s disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious with a global rise in life expectancy.
Qianqian Huang, Chen Zhang, Sihao Qu, Shi Dong, Qihong Ma, Ying Hao, Zimin Liu, Shanglong Wang, Haibin Zhao, Yuanyuan Shi, Yuanyuan Shi   +10 more
doaj   +1 more source

Illumination on “Reserving Phloem and Discarding Xylem” and Quality Evaluation of Radix polygalae by Determining Oligosaccharide Esters, Saponins, and Xanthones

Molecules, 2018
The root of Polygala tenuifolia Willd. or Polygala sibirica L. exhibits protective effects on the central nervous system and is frequently used to treat insomnia, amnesia, and other cognitive dysfunction. In our study, we studied nine bioactive compounds
Fan Yang, Huijuan Yu, Xin Chai, Siwei Peng, Junjun Yang, Dan Wu, Jie Du, Yuefei Wang   +7 more
doaj   +1 more source

Genetic diversity and population structure of a protected species: Polygala tenuifolia Willd

Comptes Rendus. Biologies, 2018
Polygala tenuifolia Willd. is an important protected species used in traditional Chinese medicine. In the present study, amplified fragment length polymorphism (AFLP) markers were employed to characterize the genetic diversity in wild and cultivated P.
Yan Qun, Peng, Ling Ling, Fan, Fu Ying, Mao, Yun Sheng, Zhao, Rui, Xu, Yu Jie, Yin, Xin, Chen, De Guang, Wan, Xin Hui, Zhang   +8 more
openaire   +2 more sources

Chemical constituents from the aerial part of Polygala tenuifolia

, 2021
Three new compounds, polygalapyrone A (1), tenuiside G (2) and polygalapyrrole A (3), together with two known compounds (4–5) were isolated by silica gel, ODS and preparative HPLC from the aerial part of Polygala tenuifolia.
Yan-Gang Cheng (8974085), Kai-Li Liu (2143282), Jin-Yan Tan (8974082), Jia-Min Wang (9100523), Ying-Li Wang (2239207), Shi-Hui Wang (2080201), Jian-Li Li (2067484)   +6 more
core   +1 more source

Pharmacology of polygala tenuifolia and its significance in traditional Chinese medicine

Pharmacological Research - Modern Chinese Medicine
Introduction: The dried root of Polygala tenuifolia Willd., known as Polygala Radix, belonging to the family Polygalaceae, has long been used as a medication to cure a variety of illnesses, including sleeplessness, forgetfulness, sadness, cough, and ...
Akash Garg, Rutvi Agrawal, Rohitas Deshmukh   +2 more
doaj   +1 more source

Response surface methodology for optimization of extracting polysaccharide from Polygala tenuifolia willd. and antioxidant evaluation

, 2016
The optimum condition of ultrasonic extraction of Polygala tenuifolia Willd. Polysaccharide (PTP) was investigated. The results showed, the optimum condition was ultrasonic extraction time 30 min, ultrasonic extraction, temperature 67 ℃, ratio of water ...
Qian, WANG, Lanfang, WU, Yuguang, ZHENG, Yongshuai, JING, Yuping, YAN, Aimin, JIANG   +5 more
core   +1 more source

Polygala L. (Polygalaceae) in Chile

, 2021
En Chile crecen cinco especies de Polygala L. (Polygalaceae), P. darwiniana A.W. Benn., P. gnidioides Willd., P. salasiana Gay, P. solieri Gay y P. subandina Phil.
Martinez, Agustina, Teillier, Sebastián
core   +1 more source

UHPLC-MS/MS method for pharmacokinetic and bioavailability determination of five bioactive components in raw and various processed products of Polygala tenuifolia in rat plasma

Pharmaceutical Biology, 2020
Context Sibiricose A5 (A5), sibiricose A6 (A6), 3,6′-disinapoyl sucrose (DSS), tenuifoliside A (TFSA) and 3,4,5-trimethoxycinnamic acid (TMCA) are the main active components of Polygala tenuifolia Willd.
Xin Zhao, Baoxin Xu, Peng Wu, Pan Zhao, Changchuan Guo, Yueli Cui, Yanxue Zhang, Xuelan Zhang, Huifen Li   +8 more
doaj   +1 more source

Xuming Zhusan Decoction Attenuates Post‐Stroke via Modulating TLR4/MYD88/NF‐κB Pathway in Mice

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
High‐dose Xuming Zhusan (XMZS) improves neurological/cognitive functions and reduces cerebral infarct in MCAO mice. It inhibits microglial activation and pro‐inflammatory cytokines via suppressing the TLR4/MYD88/NF‐κB pathway, protecting neurons. ABSTRACT Ischemic stroke induces neuroinflammation that exacerbates neuronal damage.
Xi Liu, Cheng Wang, Ling Han, Yi'an Xiao, Hanchang Yu, Zhongxu Hu, Xiyun Fei, Min Peng, Jilin Zhou, Zhijun Zhong   +9 more
wiley   +1 more source