Results 71 to 80 of about 112,263 (200)

Distribution of polygenic scores in the HPFS.

open access: yes, 2022
Distribution of the global and pathway polygenic scores in the HPFS. HPFS, Health Professionals Follow-up Study. (PNG)
Liming Liang (69800)   +15 more
core   +1 more source

The rate of polygenic mutation

open access: yesGenetical Research, 1988
SummaryBy application of the neutral model of phenotypic evolution, quantitative estimates of the rate of input of genetic variance by polygenic mutation can be extracted from divergence experiments as well as from the response of an inbred base population to selection.
openaire   +2 more sources

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder [PDF]

open access: yes, 2015
Genetic risk prediction has several potential applications in medical research and clinical practice and could be used, for example, to stratify a heterogeneous population of patients by their predicted genetic risk.
Caesar, Sian   +958 more
core   +2 more sources

Genetic markers used in the polygenic risk score calculation.

open access: yes, 2023
Genetic markers used in the polygenic risk score calculation.
Christofer Toumazou (571395)   +1 more
core   +1 more source

Polygenic traits adaptation leads to selection of beneficial alleles in local regulatory hubs

open access: yes
International audiencePolygenic traits are involved in many key processes such as adaptation to local environments in many eukaryotic species. Deciphering their genetic architecture is key for understanding how they are inherited and how they may evolve.
Fagny, Maud
core   +1 more source

Gene regulatory network structure help us understandhow polygenic phenotypes adapt

open access: yes
International audienceThe adaptation of populations to local environments often relies on the selection of optimal values for one or several polygenic phenotypes.
Platig, John   +4 more
core   +2 more sources

Interplay between polygenic risk and family processes in predicting trajectories of adolescent externalizing behaviors

open access: yesFrontiers in Psychiatry
IntroductionThere is limited understanding on how polygenic scores derived from genome-wide association studies of adult and child psychopathology may uniquely predict childhood traits.
Jinni Su   +7 more
doaj   +1 more source

Parameters and notation of polygenic model.

open access: yes, 2013
Parameters and notation of polygenic model.
Frank Dudbridge (102283)
core   +1 more source

Polygenic risk for epigenetic aging and adverse life experiences interact to predict growth in adolescent depression in a racially/ethnically diverse sample

open access: yesFrontiers in Psychiatry
IntroductionResearch has yet to examine the interplay between indices of environmental risk and resilience processes and genetic predisposition for epigenetic aging in predicting early adolescent depressive symptoms.
Kit K. Elam   +3 more
doaj   +1 more source

Geographic Clustering of Polygenic Scores at Different Stages of the Life Course

open access: yesRSF: The Russell Sage Foundation Journal of the Social Sciences, 2018
We interrogate state-level clustering of polygenic scores at different points in the life course and variation in the association of mean polygenic scores in a respondent’s state of birth with corresponding phenotypes. The polygenic scores for height and
Benjamin W. Domingue   +3 more
doaj   +1 more source

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