Results 81 to 90 of about 14,352 (184)
UBL3 Interacts with PolyQ-Expanded Huntingtin Fragments and Modifies Their Intracellular Sorting
Neurology InternationalBackground/Objectives: UBL3 (Ubiquitin-like 3) is a protein that plays a crucial role in post-translational modifications, particularly in regulating protein transport within small extracellular vesicles. While previous research has predominantly focused
Soho Oyama +19 more
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A triazole derivative elicits autophagic clearance of polyglutamine aggregation in neuronal cells
Drug Design, Development and Therapy, 2016 Chang Heng Hsieh,1 Li-Ching Lee,1 Wai-Yin Leong,1 Tsai-Chen Yang,1 Ching-Fa Yao,2 Kang Fang1 1Department of Life Science, 2Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan Abstract: Trinucleotide CAG repeat expansion in the ...
Hsieh CH +5 more
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Neurodegeration based on polyglutamine aggregation
Rinsho Shinkeigaku, 2011 One of the major hypotheses about polyQ toxicity is the sequestration of functionally important proteins into the aggregates. We established and carried out a direct, systematic proteomic analysis of aggregate-interacting proteins (AIPs). This analysis, as well as other studies in our lab, has revealed the following AIPs in addition to our previously ...
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Nutrient and heat stress induce changes to the solubility of predicted prion-like proteins in Dictyostelium discoideum. [PDF]
BMC Mol Cell BiolWilliams FN +4 more
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Exploring non-autonomous protein homeostasis driven by glutamatergic neurons. [PDF]
MicroPubl BiolHruby AJ +8 more
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