Results 21 to 30 of about 169 (141)

Characterization of a Cryptic NRPS Gene Cluster in Bacillus velezensis FZB42 Reveals a Discrete Oxidase Involved in Multithiazole Biosynthesis

, 2022
Polythiazole-containing nonribosomal peptides (NRPs) represent a rare and important group of natural products with intriguing structures and promising bioactivities.
Ming Yang (109148), Xiaoying Bian (1908739), Qiyao Shen (11204012), Zhihui Zheng (820145), Haibo Zhou (575077), Liujie Huo (2015908), Ya-Jie Tang (3482438), Nianzhi Jiao (138252), Yang Liu (4829), Aiying Li (558921), Guannan Zhong (8373858), Vinothkannan Ravichandran (5713811), Youming Zhang (565208), Guangzhi Dai (11204015)   +13 more
core   +2 more sources

Rhodacyclopentanones as Linchpins for the Atom Economical Assembly of Diverse Polyheterocycles [PDF]

Journal of the American Chemical Society, 2020
We outline a conceptual blueprint that provides direct and atom economical access to a wide range of complex polyheterocycles. Our method capitalizes on the ambiphilic reactivity of rhodacyclopentanones that arise upon exposure of cyclopropanes to Rh(I) catalysts and CO.
Gang-Wei Wang, Olivia Boyd, Tom A. Young, Sophie M. Bertrand, John F. Bower   +4 more
openaire   +3 more sources

Metathesis Approach to the Synthesis of Polyheterocyclic Structures from Oxanorbornenes [PDF]

Organic Letters, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Jeffrey D, Winkler, Sylvie M, Asselin, Stacey, Shepard, Jing, Yuan   +3 more
openaire   +2 more sources

1,2,3-Triazole in Heterocyclic Compounds, Endowed with Biological Activity, through 1,3-Dipolar Cycloadditions

, 2014
1,3-Dipolar cycloaddition reactions can be considered a powerful synthetic tool in the building of heterocyclic rings, with applications in different fields.
LAURIA, Antonino, DELISI, Riccardo, Mingoia, F, Anna Maria Almerico, Riccardo Delisi, MARTORANA, Annamaria, BARONE, Giampaolo, Francesco Mingoia, TERENZI, Alessio, Giampaolo Barone, Annamaria Martorana, Alessio Terenzi, Antonino Lauria, ALMERICO, Anna Maria   +13 more
core   +1 more source

Synthetic routes to benzimidazole-based fused polyheterocycles [PDF]

Arkivoc, 2010
The review article represents a survey covering the synthetic strategies leading to benzimidazole- based fused polyheterocyclic systems utilizing simple reactive benzimidazole synthons since 1980. The polyheterocyclic systems are classified based on the number of rings; tetra-, penta-, hexa- and hepta-fused ring systems.
Kamal M. Dawood, Bakr F. Abdel-Wahab
openaire   +1 more source

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

ChemistryEurope, Volume 4, Issue 6, June 2026.
Polycyclic intermediates enable stereocontrolled synthesis of densely functionalized cis‐1,3‐diamine and amino alcohol carbocycles and heterocycles via structural‐to‐functional complexity transformations from low‐complexity starting material. Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products ...
Jiayi Zhu, Erica Benedetti, Laurent Micouin   +2 more
wiley   +1 more source

Mo‐Catalyzed Synthesis of N‐Polyheterocycles From Functionalized Nitroarenes and Aldehydes

Asian Journal of Organic Chemistry, Volume 15, Issue 5, May 2026.
Mo(VI)‐catalyzed one‐pot conversion of readily available functionalized nitroarenes and aldehydes yielded fused N‐polyheterocycles by sequential nitro reduction, imine formation, and cyclization. Using pinacol as a benign reductant, this sustainable tandem strategy suppresses side reactions and grants rapid access to diverse pharmacologically relevant ...
Raúl Martínez‐González, Rubén Rubio‐Presa, María R. Pedrosa, Samuel Suárez‐Pantiga, Roberto Sanz   +4 more
wiley   +1 more source

Metal- and light-free approach to polyheterocycles via a quinone-Cs2CO3 couple promoted regioselective cascade radical cyclization

Green Synthesis and Catalysis
A highly efficient, transition-metal- and light-free approach to polyheterocycles via regioselective cascade radical cyclization is developed. The redox-neutral protocol has a broad substrate scope with good functional group tolerance and probably ...
Qijing Zhang, Pan Yue, Hao Lei, Cong-Ying Zhou, Chengming Wang   +4 more
doaj   +1 more source

Research on synthesis of microwave‐assisted heterocyclic compounds with eco‐friendly solvents and transition metals via C–H activation

Bulletin of the Korean Chemical Society, Volume 47, Issue 4, Page 384-395, April 2026.
This review summarizes microwave‐assisted transition‐metal catalysis for constructing N‐ and O‐heterocycles, highlighting rapid C–H and pre‐activated C–X activation, improved selectivity, and green synthetic efficiency. Abstract Microwave‐assisted organic synthesis provides a rapid and sustainable platform for synthesizing various heterocycles ...
Woo‐Jin Park, Ye Ri Han, Hyejeong Lee
wiley   +1 more source

Synthesis of Novel Dihydrothieno- and Thiopyrano Quinolines from 3-Formyl-2-Mercaptoquinoline Derivatives

, 2019
Several new fused polycyclic 2,3-dihydro-thieno[2,3-b]quinolin-3-ol derivatives were synthesis through the un-catalyzed reaction of various 2-mercaptobenzoquinoline-3-carbaldehydes with 2-bromoacetophenones in CH2Cl2 at 80–90% yield. Besides, reaction of
Zeinab Faghihi (6272588), Majid M. Heravi (3939749), Vahideh Zadsirjan (6272597), Morteza Shiri (6272591), Faghihi, Z., M Heravi; Majid, Pourabed, R., Raziyeh Pourabed (6272594), Zadsirjan, V., Shiri, M.   +9 more
core   +1 more source