Results 31 to 40 of about 916 (181)

A Zinc-Mediated Deprotective Annulation Approach to New Polycyclic Heterocycles [PDF]

open access: yes, 2021
A straightforward approach to new polycyclic heterocycles, 1H-benzo[4,5]imidazo[1,2-c][1,3]oxazin-1-ones, is presented. It is based on the ZnCl2-promoted deprotective 6-endo-dig heterocyclization of N-Boc-2-alkynylbenzimidazoles under mild conditions ...
Bartolo Gabriele   +6 more
core   +1 more source

A Short Synthesis of (±)-3-Demethoxyerythratidinone by Ligand Controlled Selective Heck Cyclization of Equilibrating Enamines [PDF]

open access: yes, 2017
A short, 5-step total synthesis of (±)-3-demethoxyerythratidinone from a simple pyrrole derivative is described. Features include the formation of gram quantities of a key tricylic aziridine from a challenging photochemical cascade reaction through the ...
Albini   +39 more
core   +2 more sources

Iron-catalyzed cascade synthesis of nitrogen polycycles from alkynoic acids and functionalized amines [PDF]

open access: yes, 2022
Catalysis by first-row transition metals is of increasing interest in the context of the scarcity of chemical resources. For instance, iron is promising due to its abundance, low toxicity and unique electronic features.
Astobieta, Elene   +6 more
core   +2 more sources

Diversity-oriented synthesis as a tool for identifying new modulators of mitosis. [PDF]

open access: yes, 2014
The synthesis of diverse three-dimensional libraries has become of paramount importance for obtaining better leads for drug discovery. Such libraries are predicted to fare better than traditional compound collections in phenotypic screens and against ...
Alza, Esther   +8 more
core   +1 more source

Metathesis Approach to the Synthesis of Polyheterocyclic Structures from Oxanorbornenes [PDF]

open access: yesOrganic Letters, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Jeffrey D, Winkler   +3 more
openaire   +2 more sources

Synthesis of New 5-Aryl-benzo[f][1,7]naphthyridines via a Cascade Process (Ugi-3CR/Intramolecular Aza-Diels-Alder Cycloaddition)/Aromatization

open access: yesMolecules, 2018
A series of eight new 5-aryl-benzo[f][1,7]naphthyridines were synthesized in 17 to 64% overall yields via an improved MW-assisted cascade-like one pot process (Ugi–three component reaction/intramolecular aza-Diels-Alder cycloaddition) coupled to an
Óscar Vázquez-Vera   +8 more
doaj   +1 more source

Novel magneto-optic behaviour from a polysquaraine [PDF]

open access: yes, 2013
Copyright © 2013 Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Synthetic Metals. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other ...
Lynch, Daniel E.   +3 more
core   +1 more source

Multicomponent reactions in diverse heterocycles synthesis and medicinal chemistry [PDF]

open access: yes, 2022
The aim of this dissertation is to discuss new protein-protein interaction target, to apply multicomponent reaction chemistry on N-heterocycle compound synthesis for medicinal chemistry and to exploit the novel scaffold modulators for malaria and cancer ...
Zhang, Bidong
core   +1 more source

Metal- and light-free approach to polyheterocycles via a quinone-Cs2CO3 couple promoted regioselective cascade radical cyclization

open access: yesGreen Synthesis and Catalysis
A highly efficient, transition-metal- and light-free approach to polyheterocycles via regioselective cascade radical cyclization is developed. The redox-neutral protocol has a broad substrate scope with good functional group tolerance and probably ...
Qijing Zhang   +4 more
doaj   +1 more source

Tris(pentafluorophenyl)borane and beyond: modern advances in borylation chemistry [PDF]

open access: yes, 2017
As main-group chemistry, in particular boron chemistry, has expanded and developed over the past 20 years, one reagent has risen to prominence as well.
James R. Lawson   +3 more
core   +2 more sources

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