Results 31 to 40 of about 517 (172)

Synthesis of New 5-Aryl-benzo[f][1,7]naphthyridines via a Cascade Process (Ugi-3CR/Intramolecular Aza-Diels-Alder Cycloaddition)/Aromatization

open access: yesMolecules, 2018
A series of eight new 5-aryl-benzo[f][1,7]naphthyridines were synthesized in 17 to 64% overall yields via an improved MW-assisted cascade-like one pot process (Ugi–three component reaction/intramolecular aza-Diels-Alder cycloaddition) coupled to an
Óscar Vázquez-Vera   +8 more
doaj   +1 more source

Privileged Substructure-Based Diversity-Oriented Synthesis Pathway for Diverse Pyrimidine-Embedded Polyheterocycles

open access: yes, 2016
A new diversity-oriented synthesis pathway for the fabrication of a pyrimidine-embedded polyheterocycles library was developed for potential interactions with diverse biopolymers.
Seung Bum Park (197493)   +2 more
core   +1 more source

Visible-Light-Promoted Cyanoalkylation/Cyclization Cascade Reaction to Assemble Polyheterocycles in Continuous Flow

open access: yes, 2023
This study describes a visible-light-induced cascade reaction for preparing cyanoalkyl-containing polyheterocycles initiated by the photoinduced radical cascade addition of N-arylacrylamide derivatives using cyclic oxime esters as radical sources ...
Shan-Shan Zhu (9925702)   +15 more
core   +1 more source

Synthesis of optically active polyheterocycles containing pyrrolidine, imidazole, and 1,2,3-triazole rings [PDF]

open access: yes, 2015
Optically active polyheterocycles containing pyrrolidine, imidazole, and 1,2,3-triazole units were obtained via a multistep synthesis with the [3+2] cycloaddition of Boc-protected (S)-(pyrrolidin-2-yl)methyl azide with 2-ethynylimidazoles in the presence
Heimgartner, Heinz   +2 more
core   +1 more source

A highly efficient synthesis of imidazo-fused polyheterocycles via Groebke–Blackburn–Bienaymè reaction catalyzed by LaCl3·7H2O

open access: yes, 2014
A highly efficient and mild protocol for the synthesis of imidazo-fused polyheterocycles via Groebke–Blackburn–Bienaymè reaction under the influence of catalytic amount of lanthanum chloride heptahydrate has been described.
Malipatel, S   +4 more
core   +1 more source

Mo‐Catalyzed Synthesis of N‐Polyheterocycles From Functionalized Nitroarenes and Aldehydes

open access: yesAsian Journal of Organic Chemistry, Volume 15, Issue 5, May 2026.
Mo(VI)‐catalyzed one‐pot conversion of readily available functionalized nitroarenes and aldehydes yielded fused N‐polyheterocycles by sequential nitro reduction, imine formation, and cyclization. Using pinacol as a benign reductant, this sustainable tandem strategy suppresses side reactions and grants rapid access to diverse pharmacologically relevant ...
Raúl Martínez‐González   +4 more
wiley   +1 more source

Poly(3-alkyltellurophene)s Are Solution-Processable Polyheterocycles

open access: yes, 2016
The synthesis and characterization of a series of poly­(3-alkyltellurophene)­s are described. Polymers are prepared by both electrochemical and Kumada catalyst transfer polymerization methods. These polymers have reasonably high molecular weights (Mn = 5.
Theresa M. McCormick (1275276)   +6 more
core   +1 more source

Research on synthesis of microwave‐assisted heterocyclic compounds with eco‐friendly solvents and transition metals via C–H activation

open access: yesBulletin of the Korean Chemical Society, Volume 47, Issue 4, Page 384-395, April 2026.
This review summarizes microwave‐assisted transition‐metal catalysis for constructing N‐ and O‐heterocycles, highlighting rapid C–H and pre‐activated C–X activation, improved selectivity, and green synthetic efficiency. Abstract Microwave‐assisted organic synthesis provides a rapid and sustainable platform for synthesizing various heterocycles ...
Woo‐Jin Park, Ye Ri Han, Hyejeong Lee
wiley   +1 more source

Access to Indole-Fused Polyheterocycles via Pd-Catalyzed Base-Free Intramolecular Cross Dehydrogenative Coupling

open access: yes, 2016
A base-free process to access indole-fused polyheterocycles via a highly efficient and atom-economic palladium-catalyzed intramolecular cross dehydrogenetive coupling (CDC) reaction of 4-aniline substituted coumarins, quinolinones, and pyrones has been ...
Chao Cheng (11274)   +3 more
core   +1 more source

Broad‐Spectrum Antiviral Agents against SARS‐CoV‐2 Variants Inhibit the Conserved Viral Protein Nsp1–RNA Interaction

open access: yesAngewandte Chemie, Volume 136, Issue 47, November 18, 2024.
The demand for robust antiviral approaches is underscored by the continued COVID‐19 spread. SARS‐CoV‐2 Nsp1, highly conserved among SARS‐CoV‐2 variants, plays a pivotal role in controlling host protein expression and viral RNA translation. A small‐molecule Nsp1 inhibitor exhibited antiviral activity against various sarbecoviruses, signifying a ...
Wan Gi Byun   +7 more
wiley   +2 more sources

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