Results 21 to 30 of about 916 (181)
Pharmaceuticals, 2022 A highly efficient approach to a new indolizine scaffold fused with pyrrolo[1,2-c]pyrimidine was achieved via one-pot three-component coupling followed by an oxidative cyclization reaction.
Seonghyeon Nam +4 more
doaj +1 more source
Chemistry Proceedings, 2021 The synthesis of five new bis-furanyl-pyrrolo[3,4-b]pyridin-5-ones in 30 to 40% yields through a domino sequence based on the Ugi-Zhu three-component reaction is described.
Ivette Morales-Salazar +5 more
doaj +1 more source
Iodine/Palladium Approaches to the Synthesis of Polyheterocyclic Compounds [PDF]
The Journal of Organic Chemistry, 2010 A simple, straightforward strategy for the synthesis of polyheterocyclic compounds (PHCs) is reported, which involves iterative cycles of palladium-catalyzed Sonogashira coupling, followed by iodocyclization using I(2) or ICl. A variety of heterocyclic units, including benzofurans, benzothiophenes, indoles, and isocoumarins, can be efficiently ...
Saurabh, Mehta, Richard C, Larock
openaire +2 more sources
Recent Applications of Quinolinium Salts in the Synthesis of Annulated Heterocycles
SynOpen, 2022 Quinoline derivatives are frequently found in natural products and biologically active compounds; however, construction of quinoline fused polyheterocycles is a challenging goal in synthetic organic chemistry.
Suven Das
doaj +1 more source
Green Synthesis and Catalysis, 2023 Disclosed herein is a novel Rh/Ag co-catalyzed SNH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.
Jiapian Huang +4 more
doaj +1 more source
Synthesis and Conformational Analysis of Naphthoxazine-Fused Phenanthrene Derivatives
Molecules, 2020 The synthesis of new phenanthr[9,10-e][1,3]oxazines was achieved by the direct coupling of 9-phenanthrol with cyclic imines in the modified aza-Friedel–Crafts reaction followed by the ring closure of the resulting bifunctional aminophenanthrols with ...
Khadija Belasri +6 more
doaj +1 more source
Hetero-Diels–Alder reactions of hetaryl and aryl thioketones with acetylenic dienophiles [PDF]
, 2015 Selected hetaryl and aryl thioketones react with acetylenecarboxylates under thermal conditions in the presence of LiClO4 or, alternatively, under high-pressure conditions (5 kbar) at room temperature yielding thiopyran derivatives.
Grzelak, Paulina +4 more
core +4 more sources
Fluorescent annulated imidazo[4,5-c]isoquinolines via a GBB-3CR/imidoylation sequence - DNA-interactions in pUC-19 gel electrophoresis mobility shift assay [PDF]
, 2022 Herein we report the development of a sequential synthesis route towards annulated imidazo[4,5-c]isoquinolines comprising a GBB-3CR, followed by an intramolecular imidoylative cyclisation.
Adam, C. R. +7 more
core +3 more sources
Chiral Sulfinamidourea and Strong Brønsted Acid–Cocatalyzed Enantioselective Povarov Reaction to Access Tetrahydroquinolines [PDF]
, 2014 This protocol describes a method for the laboratory synthesis of enantiomerically enriched, chiral tetrahydroisoquinolines through the application of a chiral sulfinamido urea catalyst for the Povarov reaction.
Jacobsen, Eric N., Xu, Hao, Zhang, Hu
core +1 more source
Dual-functionalization device for therapy through dopamine release and monitoring [PDF]
, 2018 "This is the pre-peer reviewed version of the following article: G. Fabregat, A. Giménez, A. Díaz, J. Puiggalí, C. Alemán, Macromol. Biosci. 2018, 18, 1800014 , which has been published in final form at https://doi.org/10.1002/mabi.201800014 .
Alemán Llansó, Carlos +4 more
core +2 more sources