Results 11 to 20 of about 517 (172)

Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C–H Functionalization Cascades [PDF]

open access: yesJournal of the American Chemical Society, 2021
Structurally complex benzo- and spiro-fused N-polyheterocycles can be accessed via intramolecular Pd(0)-catalyzed alkene 1,2-aminoarylation reactions. The method uses N-(pentafluorobenzoyloxy)­carbamates as the initiating motif, and this allows aza-Heck ...
Javier García-Cárceles   +2 more
exaly   +4 more sources

ELECTROOPTICAL PROPERTIES OF THIN FILMS OF POLYHETEROCYCLES

open access: yesLe Journal de Physique Colloques, 1983
Some conducting polyheterocycles prepared by electroinitiated polymerization as thin films on electrodes change color reversibly when they are electrochemically cycled. As an example, polypyrrole is synthetized in an oxidized form and may be reduced reversibly between 0 and - 0,7 volt vs SCE.
Gazard, M.   +4 more
openaire   +2 more sources

Structural‐to‐Functional Complexity Transformations Enabled by Bridged Polyheterocycles: Access to Cis‐1,3‐Diamines and Amino‐Alcohols

open access: yesChemistryEurope
Cis‐1,3‐functionalized carbocycles and saturated heterocycles are ubiquitous motifs in natural products, pharmaceuticals, and bioactive compounds.
Jiayi Zhu   +2 more
doaj   +2 more sources

Copper-Catalyzed Modular Assembly of Polyheterocycles [PDF]

open access: yesThe Journal of Organic Chemistry, 2020
Easy operation, readily accessible starting materials, and short syntheses of the privileged scaffold indeno[1,2-c]isoquinolinone were achieved by an multicomponent reaction (MCR)-based protocol via an ammonia-Ugi-four component reaction (4CR)/copper-catalyzed annulation sequence.
Qian Wang   +5 more
openaire   +3 more sources

2-Benzyl-7-(4-chlorophenyl)-3-morpholino-6-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one

open access: yesMolbank, 2023
The new polyheterocyclic compound, 2-benzyl-7-(4-chlorophenyl)-3-morpholino-6-((1-phenyl-1H-1,2,3-triazol-4-yl)methyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one, was synthesized by a sequential combination of 4-chlorobenzaldehyde, (1-phenyl-1H-1,2,3 ...
Perla Islas-Jácome   +6 more
doaj   +1 more source

Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-c]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells

open access: yesPharmaceuticals, 2022
A highly efficient approach to a new indolizine scaffold fused with pyrrolo[1,2-c]pyrimidine was achieved via one-pot three-component coupling followed by an oxidative cyclization reaction.
Seonghyeon Nam   +4 more
doaj   +1 more source

Synthesis of New bis-furanyl-pyrrolo[3,4-b]pyridin-5-ones via the Ugi-Zhu Reaction and Docking Studies on the Main Protease (MPro) from SARS-CoV-2

open access: yesChemistry Proceedings, 2021
The synthesis of five new bis-furanyl-pyrrolo[3,4-b]pyridin-5-ones in 30 to 40% yields through a domino sequence based on the Ugi-Zhu three-component reaction is described.
Ivette Morales-Salazar   +5 more
doaj   +1 more source

An Easy Access to Furan-Fused Polyheterocyclic Systems

open access: yesMolecules, 2022
Nitrostilbenes characterized by two different or differently substituted aryl moieties can be obtained from the initial ring-opening of 3-nitrobenzo[b]thiophene with amines. Such versatile building blocks couple the well-recognized double electrophilic reactivity of the nitrovinyl moiety (addition to the double bond, followed by, e.g., intramolecular ...
Alice Benzi   +6 more
openaire   +4 more sources

Mo-Catalyzed One-Pot Synthesis of N-Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent-Tuned Photophysical Properties. [PDF]

open access: yesChemistry, 2021
A catalytic domino reduction–imine formation– intramolecular cyclization–oxidation for the general synthesis of a wide variety of biologically relevant N-polyheterocycles, such as quinoxaline- and quinoline-fused derivatives, and phenanthridines, is ...
Hernández-Ruiz R   +6 more
europepmc   +2 more sources

Iodine/Palladium Approaches to the Synthesis of Polyheterocyclic Compounds [PDF]

open access: yesThe Journal of Organic Chemistry, 2010
A simple, straightforward strategy for the synthesis of polyheterocyclic compounds (PHCs) is reported, which involves iterative cycles of palladium-catalyzed Sonogashira coupling, followed by iodocyclization using I(2) or ICl. A variety of heterocyclic units, including benzofurans, benzothiophenes, indoles, and isocoumarins, can be efficiently ...
Saurabh, Mehta, Richard C, Larock
openaire   +2 more sources

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