Results 41 to 50 of about 916 (181)

1,3-Dicarbonyl compounds in stereoselective domino and multicomponent reactions

, 2010
International audienceModern organic synthesis focuses on the discovery and the development of stereoselective multiple bond-forming transformations allowing the creation of several covalent bonds in a single operation.
Bonne, Damien, Constantieux, Thierry, Coquerel, Yoann, Rodriguez, Jean   +3 more
core   +4 more sources

Dynamics of Quasi-ordered Structure in a Regio-regulated pi-Conjugated Polymer:Poly(4-methylthiazole-2,5-diyl)

, 2004
Dynamics of regio-regulated Poly(4-methylthiazole-2,5-diyl) [HH-P4MeTz] was inves tigated by solid-state 1H, 2D, 13C NMR spectroscopies, and differential scanning calorimetry(DSC) measurements.
D. C. Ailion, E. R. Andrew, F. Milia, J. I. Nanos, J.-W. van der Horst, K. Schmidt-Rohr, L. Muntean, N. Asakawa, Naoki Asakawa, R. Blinc, R. D. McCullough, R. D. McCullough, R. R. Ernst, Seiichiro Mori, T. Yamamoto, T. Yamamoto, T. Yamamoto, T. Yamamoto, T. Yamamoto, Takakazu Yamamoto, W. R. Salaneck, Yoshio Inoue   +21 more
core   +1 more source

Mo‐Catalyzed Synthesis of N‐Polyheterocycles From Functionalized Nitroarenes and Aldehydes

Asian Journal of Organic Chemistry, Volume 15, Issue 5, May 2026.
Mo(VI)‐catalyzed one‐pot conversion of readily available functionalized nitroarenes and aldehydes yielded fused N‐polyheterocycles by sequential nitro reduction, imine formation, and cyclization. Using pinacol as a benign reductant, this sustainable tandem strategy suppresses side reactions and grants rapid access to diverse pharmacologically relevant ...
Raúl Martínez‐González, Rubén Rubio‐Presa, María R. Pedrosa, Samuel Suárez‐Pantiga, Roberto Sanz   +4 more
wiley   +1 more source

Research on synthesis of microwave‐assisted heterocyclic compounds with eco‐friendly solvents and transition metals via C–H activation

Bulletin of the Korean Chemical Society, Volume 47, Issue 4, Page 384-395, April 2026.
This review summarizes microwave‐assisted transition‐metal catalysis for constructing N‐ and O‐heterocycles, highlighting rapid C–H and pre‐activated C–X activation, improved selectivity, and green synthetic efficiency. Abstract Microwave‐assisted organic synthesis provides a rapid and sustainable platform for synthesizing various heterocycles ...
Woo‐Jin Park, Ye Ri Han, Hyejeong Lee
wiley   +1 more source

Broad‐Spectrum Antiviral Agents against SARS‐CoV‐2 Variants Inhibit the Conserved Viral Protein Nsp1–RNA Interaction

Angewandte Chemie, Volume 136, Issue 47, November 18, 2024.
The demand for robust antiviral approaches is underscored by the continued COVID‐19 spread. SARS‐CoV‐2 Nsp1, highly conserved among SARS‐CoV‐2 variants, plays a pivotal role in controlling host protein expression and viral RNA translation. A small‐molecule Nsp1 inhibitor exhibited antiviral activity against various sarbecoviruses, signifying a ...
Wan Gi Byun, Minha Lee, Meehyun Ko, Ji Hyae Lee, Sihyeong Yi, JinAh Lee, Seungtaek Kim, Seung Bum Park   +7 more
wiley   +2 more sources

Engineering of indole-based tethered biheterocyclic alkaloid meridianin into β-carboline-derived tetracyclic polyheterocycles via amino functionalization/6-endo cationic π-cyclization

Beilstein Journal of Organic Chemistry, 2012
A mild, efficient and versatile method has been developed for the construction of a functionalized natural product, meridianin, and its post conversion to pyrimido-β-carboline by cationic π- cyclization. The strategy involves the introduction of an amino
Piyush K. Agarwal, Meena D. Dathi, Mohammad Saifuddin, Bijoy Kundu   +3 more
doaj   +1 more source

Molybdenum-Catalyzed Synthesis of Nitrogenated Polyheterocycles from Nitroarenes and Glycols with Reuse of Waste Reduction By-product [PDF]

, 2017
A novel domino reduction/imine formation/intramolecular cyclization/oxidation for the efficient synthesis of pyrrolo(indolo)[1,2-a]quinoxalines and pyrrolo(indolo)[3,2-c]-quinolines from readily available nitrobenzenes and glycols is reported.
Arnáiz García, Francisco Javier, Fernández Rodríguez, Manuel A., Pedrosa Sáez, María de los Remedios, Rubio Presa, Rubén, Sanz Díez, Roberto   +4 more
core   +1 more source

Multicomponent Synthesis of Fluorine‐Containing Bioactive Compounds and Drugs

European Journal of Organic Chemistry, Volume 28, Issue 38, October 15, 2025.
Multicomponent reactions are robust synthetic tools to assamble complex polyheterocycles and other interesting molecular architectures with potential application in medicinal chemistry, including their fluorine‐containing analogues. Fluorine atoms placed strategically into bioactive molecules often enhance essential pharmacokinetic parameters like ...
Ivette Morales‐Salazar, Perla Islas‐Jácome, Leonardo D. Herrera‐Zuñiga, Samuel Couve‐Bonnaire, Philippe Jubault, Eduardo González‐Zamora, Jean‐Philippe Bouillon, Alejandro Islas‐Jácome   +7 more
wiley   +1 more source

ELECTROOPTICAL PROPERTIES OF THIN FILMS OF POLYHETEROCYCLES

Le Journal de Physique Colloques, 1983
Some conducting polyheterocycles prepared by electroinitiated polymerization as thin films on electrodes change color reversibly when they are electrochemically cycled. As an example, polypyrrole is synthetized in an oxidized form and may be reduced reversibly between 0 and - 0,7 volt vs SCE.
Gazard, M., Dubois, J, Champagne, M., Garnier, F., Tourillon, G.   +4 more
openaire   +1 more source

One‐Pot Three‐Component Coupling Access to Indolizine‐Pyrrolodiazepine Hybrid Structures

Asian Journal of Organic Chemistry, Volume 14, Issue 6, June 2025.
One‐pot three‐component coupling of pyridine‐2‐acetonitrile, N‐substituted pyrrole‐2‐carboxaldehyde, and TMSCN in the presence of DBU allowed facile access to a novel indolizine‐pyrrolodiazepine hybrid structure via a domino aldol condensation‐Michael addition‐cycloisomerization‐imine formation process enabling sequential construction of two ...
Sunhee Lee, Seonghyeon Nam, Ikyon Kim
wiley   +1 more source