Results 151 to 160 of about 4,367 (175)

Interaction of polyhexamethylene biguanide hydrochloride (PHMB) with phosphatidylcholine containing o/w emulsion and consequences for microbicidal efficacy and cytotoxicity

Chemico-Biological Interactions, 2013
Oil-in-water (o/w) emulsions containing egg yolk phosphatidylcholine (EPC) were combined with aqueous polyhexamethylene biguanide hydrochloride (PHMB). The PHMB concentration in the aqueous phase was estimated by filtration centrifugation experiments. In parallel, PHMB concentration was assessed utilizing cytotoxicity assays (neutral red) on cultured ...
Axel Kramer, Gerald Müller
exaly   +3 more sources

Contact allergy to polyhexamethylene biguanide (polyaminopropyl biguanide)

Contact Dermatitis, 2021
Background: Polyaminopropyl biguanide (INCI name) and polyhexamethylene biguanide (PHMB) are polymeric biguanides. PHMB is a broad-spectrum antimicrobial substance used as a preservative in many products.
Nils Hamnerius, Magnus Bruze, Annarita Antelmi   +2 more
exaly   +2 more sources

In-vitro activity of polyhexamethylene biguanide (PHMB) against fungal isolates associated with infective keratitis

Journal of Antimicrobial Chemotherapy, 1999
Majid Moshirfar, Susan L Pendland
exaly   +3 more sources

Polyhexamethylene Biguanide:Polyurethane Blend Nanofibrous Membranes for Wound Infection Control [PDF]

Polymers, 2019
Polyhexamethylene biguanide (PHMB) is a broad-spectrum antiseptic which avoids many efficacy and toxicity problems associated with antimicrobials, in particular, it has a low risk of loss of susceptibility due to acquired antimicrobial resistance ...
Janice Tsui, Wenhui Song, Anna Worsley   +2 more
exaly   +2 more sources

Polyhexamethylene biguanide hydrochloride (PHMB)-properties and application of an antiseptic agent. A narrative review

European Journal of Ophthalmology, 2022
The prevention and management of ocular surface infections is still one of the great challenges for ophthalmologists. The spread of antimicrobial resistance makes it necessary to use antiseptic substances with a broad antimicrobial spectrum. Polyhexamethylene biguanide hydrochloride (Polyhexanide, PHMB) is a broad-spectrum antiseptic with excellent ...
Alfredo Niro, Francesco Pignatelli, Matteo Fallico, Alessandra Sborgia, Fedele Passidomo, Samuele Gigliola, Annalisa Nacucchi, Giancarlo Sborgia, Giacomo Boscia, Giovanni Alessio, Francesco Boscia, Giuseppe Addabbo, Michele Reibaldi, Teresio Avitabile   +13 more
openaire   +3 more sources

Cooperativity in the binding of the cationic biocide polyhexamethylene biguanide to nucleic acids

Biochemical and Biophysical Research Communications, 2004
The interaction between the broad-spectrum antimicrobial agent, polyhexamethylene biguanide (PHMB), and various nucleic acids was investigated. Titration of either single- or double-stranded 100-bp DNA, or mixed-molecular weight marker DNA, or tRNA with ...
Michael Allen, Graham F White
exaly   +2 more sources

Optimization of flow dynamics in single-pass and recirculating systems for enhanced Escherichia coli removal efficiency using polyhexamethylene biguanide (PHMB) modified PAN-based nanofiber membranes

Separation and Purification Technology
Penjit Srinophakun, Chen-Yaw Chiu, Yu-Kaung Chang   +2 more
exaly   +2 more sources

Polyhexamethylene Biguanide (PHMB): An Addendum to Current Topical Antimicrobials.

Wounds : a compendium of clinical research and practice, 2015
Antimicrobials are routinely used in the treatment of chronic and problematic wounds. Despite the on-going increase in numbers and types of products, well-designed clinical trials that support their efficacy are limited. Antimicrobial products are applied with understanding of their mechanisms of action and role in wound repair. This manuscript reviews
Gerit D, Mulder, Joseph P, Cavorsi, Daniel K, Lee   +2 more
openaire   +1 more source

[Preventing nosocomial infections. Dressings soaked in polyhexamethylene biguanide (PHMB)].

Revista de enfermeria (Barcelona, Spain), 2006
Polyhexamethlene biguanide (PHMB) is an antibacterial agent included in the chlorhexidine group which is active against a wide number of microorganisms including Staphylococcus Aureus Methycilin Resistant (MRSA), Vancomycin Resistant Enterococcus Faecalis (VRE) and Acinetobacter baumannii which all cause antibiotic-resistant infections.
Luis, Salas Campos, Ona, Gómez Ferrero, Vanesa, Estudillo Pérez, Marta, Fernández Mansilla   +3 more
openaire   +1 more source

NCW2, a Gene Involved in the Tolerance to Polyhexamethylene Biguanide (PHMB), May Help in the Organisation of β-1,3-Glucan Structure of Saccharomyces cerevisiae Cell Wall

Current Microbiology, 2016
In the present work, we provide biological evidences supporting the participation of NCW2 gene in the mechanism responsible for cell tolerance to polyhexamethylene biguanide (PHMB), an antifungal agent. The growth rate of yeast cells exposed to this agent was significantly reduced in ∆ncw2 strain and the mRNA levels of NCW2 gene in the presence of PHMB
Carolina, Elsztein, Rita de Cássia Pereira, de Lima, Will, de Barros Pita, Marcos Antonio, de Morais   +3 more
openaire   +2 more sources