Results 61 to 70 of about 4,367 (175)

Analysis of povidone iodine, chlorhexidine acetate and polyhexamethylene biguanide as wound disinfectants: in vitro cytotoxicity and antibacterial activity

BMJ Nutrition, Prevention & Health, 2023
Objectives Even though disinfectants are commonly used in clinical practice and daily life, there are few studies on their antibacterial ability and cytotoxicity, which are closely related to the safety and effectiveness of their use.
WANG Guang-Yi, Mingshi Zhang, Jian Jin, Yingying Liu, Chi Ben, Haihang Li, Dasheng Cheng, Shihui Zhu   +7 more
doaj   +1 more source

Oxygen and ROS Delivery for Infected Wound Healing and Future Prospects

Advanced Healthcare Materials, Volume 15, Issue 15, 17 April 2026.
Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.
Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet   +7 more
wiley   +1 more source

Evaluation of Amebicidal and Cysticidal Activities of Antifungal Drug Isavuconazonium Sulfate against Acanthamoeba T4 Strains

Pharmaceuticals, 2021
Acanthamoeba species of amebae are often associated with Acanthamoeba keratitis, a severe corneal infection. Isavuconazonium sulfate is an FDA-approved drug for the treatment of invasive aspergillosis and mucormycosis.
Brian Shing, Mina Balen, Anjan Debnath
doaj   +1 more source

In Vitro and In Vivo Comparison of a Novel Antimicrobial Wound Hydrogel With Commercial Wound Treatments: Antimicrobial, Antibiofilm and Biocompatibility Assessment

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Antimicrobial resistance (AMR) and biofilm formation significantly hinder chronic wound management, necessitating safer and more effective therapeutic options. This study evaluates the antimicrobial, antibiofilm, cytocompatibility and anti‐inflammatory properties of a novel antimicrobial hydrogel Formulation (#1) compared with commercially ...
Melika Moradi, Ali Pormohammad, Charline Luong, Raymond J. Turner   +3 more
wiley   +1 more source

Determination of Minimum Inhibitory Concentration (MIC) of a PolyHexamethylene Biguanide (PHMB) Solution: A Potential Root Canal Irrigant

Annual Research & Review in Biology, 2017
Background: A polymeric biguanide ‘PolyHexaMethylene Biguanide’ (PHMB) was evaluated for its Minimal Inhibitory Concentration (MIC) against ATCC reference laboratory strain of Enterococcus faecalis (E. faecalis).Methods: The MIC was determined using criteria’s laid down in DIN 58940-7 and 58940-8 and the corresponding supplementary sheets.
Rita, Chandki, Nikhil, Vineeta, Surapaneni, Sai Kalyan   +2 more
openaire   +2 more sources

Implementing Wound Hygiene in the Italian Healthcare Context: Expert Recommendations for the Management of Venous Leg Ulcers

International Wound Journal, Volume 23, Issue 3, March 2026.
ABSTRACT The ‘Wound Hygiene Italia’ project was designed to provide expert‐driven recommendations for the assessment, management and monitoring of venous leg ulcers, tailored to diverse settings of care (hospital, ambulatory and home care). The recommendations, developed by a multidisciplinary panel, emphasise the implementation of the Wound Hygiene ...
Alessandro Scalise, Franco Bassetto, Diego Ceci, Guido Ciprandi, Deborah Cesura Granara, Barbara De Angelis, Ciro Falasconi, Domitilla Foghetti, Francesco Giacinto, Alessandro Greco, Filippo Magnoni, Marco Marchelli, Giuseppe Nebbioso, Battistino Paggi, Giovanni Papa, Francesco Petrella, Salvatore Piazza, Marco Romanelli, Elia Ricci, Sara Sandroni   +19 more
wiley   +1 more source

Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis

Frontiers in Microbiology, 2017
Staphylococcus aureus infection is a common cause of mastitis, reducing milk yield, affecting animal welfare and causing huge economic losses within the dairy industry. In addition to the problem of acquired drug resistance, bacterial invasion into udder
Nor F. Kamaruzzaman, Stacy Q. Y. Chong, Kamina M. Edmondson-Brown, Winnie Ntow-Boahene, Marjorie Bardiau, Liam Good   +5 more
doaj   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Preparation and Antimicrobial Activity of a Film-Forming Polyhexamethylene Biguanide Teat Disinfectant

, 2023
Bovine mastitis caused by infectious pathogens can lead to a decline in production performance and an increase in elimination rate, resulting in huge losses to the dairy industry.
Dongping Zeng, Yixing Lu, Jiaxuan Lu, Yueying Hu, Yongxiang Zhang, Zhenling Zeng, Di Wang   +6 more
core   +1 more source

Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis

Acta Ophthalmologica, Volume 104, Issue 1, Page 44-51, February 2026.
Abstract Purpose Acanthamoeba keratitis (AK) is a severe corneal infection with potential detrimental effects on visual outcome and quality of life, primarily affecting young contact lens wearers. We report Acanthamoeba genotypes, subtypes and clinical outcome from Danish patients with AK. Methods Thirty‐nine PCR‐positive AK cases diagnosed and treated
Sandra M. Skovdal, Christen Rune Stensvold, Henrik Vedel Nielsen, Stine Elkjær Nielsen, Jesper Hjortdal, Anders Ivarsen   +5 more
wiley   +1 more source