Results 41 to 50 of about 4,367 (175)

A Vehicle‐Free Antimicrobial Polymer Hybrid Gold Nanoparticle as Synergistically Therapeutic Platforms for Staphylococcus aureus Infected Wound Healing

Advanced Science, 2022
Pathogenic bacteria infection is a serious threat to human public health due to the high morbidity and mortality rates. Nano delivery system for delivering antibiotics provides an alternative option to improve the efficiency compared to conventional ...
Xiaojun He, Lixiong Dai, Lisong Ye, Xiaoshuai Sun, Obeng Enoch, Rongdang Hu, Xingjie Zan, Feng Lin, Jianliang Shen   +8 more
doaj   +1 more source

Functionalized-AgNPs for Long-Term Stability and Its Applicability in the Detection of Manganese Ions

Advances in Polymer Technology, 2020
In this study, silver nanoparticles (AgNPs) were functionalized by various molecules, including sodium borohydride (NaBH4), polyhexamethylene biguanide hydrochloride (PHMB), and Tween 80 to investigate the long-term stabilization of AgNPs in an aqueous ...
Van-Tuan Hoang, Mai Mai, Le Thi Tam, Ngoc Phan Vu, Nguyen Tien Khi, Phuong Dinh Tam, Tran Quang Huy, Anh-Tuan Le, Ngo Xuan Dinh, Vinh-Hoang Tran   +9 more
doaj   +1 more source

Treatment of Nocardia asteroides keratitis with polyhexamethylene biguanide

, 1997
Purpose: Polyhexamethylene biguanide (PHMB) is a polymeric biguanide disinfectant that has been used previously in the treatment of Acanthamoeba keratitis. The authors report the first case of Nocardia asteroides keratitis treated successfully with PHMB.
Belyea, D. A., McEvoy, P., Lin, J. C., Kramer, K. K., Ward, T. P.   +4 more
core   +1 more source

Safety assessment of Polyhexamethylene biguanide [PDF]

International Journal of Medical Device and Adjuvant Treatments, 2019
OBJECTIVE: The use of antiseptics in the treatment of genital infections has become a systematic alternative to antibiotics. Their use has been also supported for the treatment of virus-induced genital infections.
B. Orrù, P. Lista, M. Bertelli, V. Unfer   +3 more
doaj   +1 more source

Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review

Membranes, 2022
The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj   +1 more source

IgE‐mediated chlorhexidine allergy—Cross‐reactivity with other biguanide disinfectants [PDF]

, 2020
: Background Chlorhexidine (CHX) is a widely utilized disinfectant that can cause IgE-mediated urticaria/anaphylaxis. The cross-reactivity of patients with IgE-mediated CHX allergy with other disinfectants, which share structural similarities with CHX ...
Suran L. Fernando, Buenter, Antonia, Gupta, Nisha, Mueller-Wirth, Nicole, Antonia Buenter, Hausmann, Oliver, Didier G. Ebo, Fernando, Suran L., Glatz, Martin, Nicole Mueller‐Wirth, Martin Glatz, Ebo, Didier G., Werner J. Pichler, Ebo, Didier, Helbling, Arthur, Mueller‐Wirth, Nicole, Oliver Hausmann, Lukas Jörg, David Spoerl, Spoerl, David, Nisha Gupta, Arthur Helbling, Jorg, Lukas, Pichler, Werner J.   +23 more
core   +1 more source

Antibacterial Hydrogels Derived from Poly(γ-glutamic acid) Nanofibers

Gels, 2022
Biocompatible hydrogels with antibacterial properties derived from γ-polyglutamic acid (γ-PGA) were prepared from bulk and electrospun nanofibers.
Hamidreza Kasbiyan, Omid Yousefzade, Estelle Simiand, Núria Saperas, Luis J. del Valle, Jordi Puiggalí   +5 more
doaj   +1 more source

Chlorhexidine 0.02% or polyhexamethylene biguanide 0.02% as the main treatment for Acanthamoeba keratitis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report medical cure and treatment failure rates of Acanthamoeba keratitis (AK) with respect to type of treatment, disease stage and prognostic factors. Methods Electronic records were reviewed for 45 patients with PCR‐positive AK treated at the Department of Ophthalmology, Aarhus University Hospital, Denmark from 2012 to 2025 ...
Anders Ivarsen, Sandra M. Skovdal, Stine Elkjær Nielsen, Christen Rune Stensvold, Henrik Vedel Nielsen, Jesper Hjortdal   +5 more
wiley   +1 more source

Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus [PDF]

, 2018
The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is ...
Kamaruzzaman, N, Chivu, A, Good, L, Pina, M   +3 more
core   +2 more sources

Polyhexanide (PHMB) – properties and applications in medicine

European Journal of Biological Research, 2020
Polyhexamethylene biguanide (PHMB) is one of the many antiseptics available in the medicine. It stands out from the others with its numerous advantages.
Patrycja Szkołuda, Tomasz M. Karpiński
doaj