Monotherapy with PHMB 0.08% as “Switch Treatment” in Complex Cases of Acanthamoeba Keratitis: A Report of Two Cases [PDF]
Case Reports in OphthalmologyIntroduction: The aim of the study was to describe the favorable clinical outcomes of 2 patients with acanthamoeba keratitis (AK) following penetrating keratoplasty (PK), successfully managed with polyhexamethylene biguanide (PHMB) 0.08 ...
Eleftherios Chatzimichail +4 more
doaj +2 more sources
Management of Severe Pediatric Lower Lip Defect After Canine Bite with Polyhexamethylene Biguanide (PHMB), Full-Thickness Skin Graft (FTSG) and Compression Foam: A Case Report. [PDF]
Children (Basel)Introduction: Pediatric lower-lip dog bite injuries are challenging due to contamination, tissue loss, and the need to maintain function, appearance, and psychological well-being. This single case describes immediate definitive closure using sharp debridement with adjunct polyhexanide (PHMB), a full-thickness skin graft (FTSG), and a polyurethane (PU ...
Lőrincz A +6 more
europepmc +3 more sources
Double-Biguanide Therapy for Resistant Acanthamoeba Keratitis
Case Reports in Ophthalmology, 2011 Aims: To report the clinical and diagnostic findings of a patient with Acanthamoeba keratitis resistant to both polyhexamethylene biguanide (PHMB)-hexamidine and chlorhexidine-hexamidine treatment.
Giulio Ferrari +2 more
doaj +2 more sources
The effect of the disulfideisomerase domain containing protein in the defense against polyhexamethylene biguanide of highly tolerant Acanthamoeba at the trophozoite stage [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2016 Acanthamoeba castellanii is a free-living protozoan pathogen capable of causing a blinding keratitis and fatal granulomatous encephalitis. Current treatment generally involves an hourly application of polyhexamethylene biguanide (PHMB) over a period of ...
Fu-Chin Huang +5 more
doaj +2 more sources
A PHMB-Functionalized Fully Absorbable Synthetic Matrix as a Novel Alternative to Biologics: Balancing Antibacterial Efficacy, Tissue Repair, and Safety [PDF]
BioengineeringEffective management of acute, complex, and chronic wounds requires constructs that simultaneously support tissue repair and provide sustained infection control.
Sean Chen +4 more
doaj +2 more sources
Microorganisms, 2022 In recent years, a rise in the number of contact lens users in the UK and worldwide coincided with an increased incidence of microbial keratitis. The aim of this study was to investigate the antimicrobial activities of polyhexamethylene guanidine (PHMG),
Dharanga Ratnayake +3 more
doaj +1 more source
Acanthamoeba Keratitis After Laser-Assisted In Situ Keratomileusis (LASIK) Successfully Treated With Polyhexamethylene Biguanide (PHMB) 0.08% Monotherapy: A Case Report. [PDF]
CureusBaker D +3 more
europepmc +2 more sources
, 2011 Dans l’industrie agro-alimentaire, l’adhésion de micro-organismes altérants ou pathogènes sur les surfaces induit des effets néfastes à la fois en termes de qualité, d’hygiène et de santé publique. Les vêtements professionnels constituent un des vecteurs de contamination par le personnel.
Chadeau, Élise
openaire +2 more sources
Polyhexanide as a new antiseptic composition for a dentist
Эндодонтия Today, 2021 Aim. To assess systematically the available scientific evidence about clinical response of using polyhexanide as an antiseptic agent in medicine and dentistry.
Z. S. Khabadze +5 more
doaj +1 more source
Membranes, 2023 Wound infection is a common complication of chronic wounds. It can impair healing, which may not occur without external help. Antimicrobial dressings (AMDs) are a type of external help to infected chronic wounds.
Luís M. Vaz +3 more
doaj +1 more source