Results 11 to 20 of about 4,367 (175)

Polyhexamethylene Biguanide Nanoparticles Inhibit Biofilm Formation by Mastitis-Causing Staphylococcus aureus [PDF]

Veterinary Sciences
Staphylococcus aureus is a mastitis pathogen that compromises cow health and causes significant economic losses in the dairy industry. High antimicrobial resistance and biofilm formation by S. aureus limit the efficacy of conventional treatments.
Renata de Freitas Leite, Breno Luis Nery Garcia, Kristian da Silva Barbosa, Thatiane Mendes Mitsunaga, Carlos Eduardo Fidelis, Bruna Juliana Moreira Dias, Renata Rank de Miranda, Valtencir Zucolotto, Liam Good, Marcos Veiga dos Santos   +9 more
doaj   +3 more sources

The dltC gene contributes to polyhexamethylene biguanide resistance in Staphylococcus aureus [PDF]

Frontiers in Microbiology
As the efficacy of conventional antibiotics continues to decline due to antibiotic resistance, there is an urgent need for alternative antimicrobial strategies.
Chenyang Guo, Congcong Wang, Qihui Chen, Sophia Hao Zheng, Fengji Zhang, Jiayu Yan, Haoyang Brady Long, Jing Luo, Xiaoyan Xuan, Peng Wang, Huaixin Zheng   +10 more
doaj   +4 more sources

Insights into the Polyhexamethylene Biguanide (PHMB) Mechanism of Action on Bacterial Membrane and DNA: A Molecular Dynamics Study [PDF]

The Journal of Physical Chemistry B, 2020
Abstract Polyhexamethylene biguanide (PHMB) is a cationic polymer with antimicrobial and antiviral properties. It has been commonly accepted that the antimicrobial activity is due the ability of PHMB to perforate the bacterial phospholipid membrane leading ultimately to its death.
Sowlati-Hashjin, Shahin, Carbone, Paola, Karttunen, Mikko   +2 more
openaire   +3 more sources

Determination of Polyhexamethylene Biguanide Hydrochloride Using a Lactone-Rhodamine B-Based Fluorescence Optode

Molecules, 2020
A new determination method for polyhexamethylene biguanide hydrochloride (PHMB) using a lactone-rhodamine B (L-RB) based fluorescence optode has been developed.
Akane Funaki, Yuta Horikoshi, Teruyuki Kobayashi, Takashi Masadome   +3 more
doaj   +2 more sources

Antimicrobial activity of polyhexamethylene biguanide nanoparticles against mastitis-causing Staphylococcus aureus [PDF]

JDS Communications, 2021
Postmilking teat disinfection is one of the main measures used to prevent mastitis caused by contagious pathogens, such as Staphylococcus aureus. The present study evaluated the antimicrobial activity of polyhexamethylene biguanide (PHMB) and PHMB ...
R.F. Leite, J.L. Gonçalves, A. Buanz, C. Febraro, D. Craig, S. Van Winden, L. Good, M.V. Santos   +7 more
doaj   +3 more sources

Dual Crosslinked Ion-Based Bacterial Cellulose Composite Hydrogel Containing Polyhexamethylene Biguanide

Membranes, 2022
Composite bacterial cellulose (BC) based hydrogel with alginate (A) or pectin (P) or alginate and pectin was fabricated via a physical crosslinking technique using calcium chloride (CaCl2) solution and incorporated with polyhexamethylene biguanide (PHMB)
Baramee Chanabodeechalermrung, Tanpong Chaiwarit, Sarana Rose Sommano, Pornchai Rachtanapun, Nutthapong Kantrong, Chuda Chittasupho, Pensak Jantrawut   +6 more
doaj   +2 more sources

Antimicrobial effectiveness of polyhexamethylene biguanide on Enterococcus faecalis, Staphylococcus epidermidis and Candida albicans [PDF]

Medicinski Glasnik, 2018
Aim To evaluate the antimicrobial activity of 0.2% polyhexamethilene biguanide (PHMB) in root canal models infected with Enterococcus faecalis, Candida albicans and Staphylococcus epidermidis. PHMB was compared in these tests with 2.5% NaOCl and 0.2% CHX.
Ivana Medvedec Mikić, Livia Cigić, Darko Kero, Danijela Kalibović Govorko, Goranka Prpić Mehičić, Arjana Tambić Andrašević, Paris Simeon   +6 more
doaj   +3 more sources

Ecotoxicity of polyhexamethylene biguanide hydrochloride (PHMB) in the neotropical snail Biomphalaria glabrata (Say, 1818) [PDF]

Anais da Academia Brasileira de Ciências
The polyhexamethylene biguanide hydrochloride (PHMB) is a sanitizer with a broad range of potential applications. Nevertheless, the ecotoxicity of PHMB to gastropod snails remains scarce.
WALLACE N. DE JESUS, MARIA EDUARDA A. ALMEIDA, MARIA CLARA S. RAMOS, KARINE B. MACHADO, THIAGO L. ROCHA, LUCIANA DAMACENA-SILVA   +5 more
doaj   +4 more sources

A Multicenter, Real-World Experience with Polyhexamethylene Biguanide (PHMB) 0.08% Monotherapy for Treating Acanthamoeba Keratitis: A Retrospective Review of 39 Cases. [PDF]

Ophthalmol Ther
Introduction: Topical polyhexamethylene biguanide (PHMB) 0.08% (AKANTIOR®, SIFI Italy) is the only licensed medicinal product for the treatment of Acanthamoeba keratitis (AK), demonstrating an 84.9% cure rate in a pivotal clinical trial. This study aimed to evaluate its effectiveness and safety in a routine clinical practice.
Knutsson KA, Di Zazzo A, Pedrotti E, Rama P, Romano V, Roszkowska AM, Triolo G, Aiello F, De Angelis S, Mencucci R, Aragona P, Birattari F, Bonacci E, Buzzi M, Coassin M, Fasolo A, Gari M, Leon P, Nucci C, Paganoni G, Pederzolli M, Secchi F, Vaccaro S, Papa V, Franch A.   +24 more
europepmc   +3 more sources

Use of polyhexamethylene biguanide on wound healing in dogs [PDF]

Acta Cirúrgica Brasileira
Purpose: To analyze the effects of polyhexamethylene biguanide (PHMB) on healing of clean surgical wounds in dogs. Methods: Thirty healthy, non-neutered dogs of different breeds underwent elective ovariohysterectomy or orchiectomy, and a 1-cm circular ...
João Vitor dos Santos Alves da Silva, Brenda Mendonça de Alcântara, Natália Helena Meneguin, Sergio Andrés Millán Guaita, Tryssia Scalon Magalhães Moi, Gabriel João Unger Carra, Josiane Morais Pazzini, Bruno Watanabe Minto   +7 more
doaj   +3 more sources