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Mechanistic Insights on Metformin and Arginine Implementation as Repurposed Drugs in Glioblastoma Treatment. [PDF]

open access: yesInt J Mol Sci
Barciszewska AM   +5 more
europepmc   +1 more source

Biguanide-functionalized peptide mimics effectively combat drug-resistant ESKAPE pathogens and meningitis. [PDF]

open access: yesNat Commun
Jiang W   +12 more
europepmc   +1 more source

Oleanolic acid acetate attenuates polyhexamethylene guanidine phosphate-induced pulmonary inflammation and fibrosis in mice

open access: yesRespiratory Physiology and Neurobiology, 2018
Oleanolic acid acetate (OAA), triterpenoid compound isolated from Vigna angularis (azuki bean), has been revealed anti-inflammatory in several studies.
Min-Seok Kim   +2 more
exaly   +6 more sources
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Polyhexamethylene guanidine phosphate-induced necrosis may be linked to pulmonary fibrosis

Toxicology Letters, 2022
Following the humidifier disinfectant incident in Korea, polyhexamethylene guanidine phosphate (PHMG-P) has been used to establish lung fibrosis model animals. Herein, we investigated time-dependent changes after a single PHMG-P instillation (22 μg/lung)
Min-Sung Kang   +2 more
exaly   +4 more sources

Polyhexamethylene guanidine phosphate aerosol particles induce pulmonary inflammatory and fibrotic responses

open access: yesArchives of Toxicology, 2015
Polyhexamethylene guanidine (PHMG) phosphate was used as a disinfectant for the prevention of microorganism growth in humidifiers, without recognizing that a change of exposure route might cause significant health effects. Epidemiological studies reported that the use of humidifier disinfectant containing PHMG-phosphate can provoke pulmonary fibrosis ...
Ha Ryong Kim   +2 more
exaly   +4 more sources

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