Results 111 to 120 of about 2,197 (135)
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Regulatory Toxicology and Pharmacology, 2019
Polyhexamethylene guanidine phosphate (PHMG-P) has effective antimicrobial activity against various microorganisms and has been widely used as a biocide in commercial products.
Ji-Seong Jeong +2 more
exaly +4 more sources
Polyhexamethylene guanidine phosphate (PHMG-P) has effective antimicrobial activity against various microorganisms and has been widely used as a biocide in commercial products.
Ji-Seong Jeong +2 more
exaly +4 more sources
Journal of Hazardous Materials
Polyhexamethylene guanidine-phosphate (PHMG-p) is a main compound used as a humidifier disinfectant, but the systemic health effects of PHMG-p still need to be explored. The circulatory and blood system is the organ that comes into contact with compounds
Sungbin Choi, Eun-Hye Kim
exaly +4 more sources
Polyhexamethylene guanidine-phosphate (PHMG-p) is a main compound used as a humidifier disinfectant, but the systemic health effects of PHMG-p still need to be explored. The circulatory and blood system is the organ that comes into contact with compounds
Sungbin Choi, Eun-Hye Kim
exaly +4 more sources
Chemico-Biological Interactions, 2019
Epidemiological and toxicological studies indicate that polyhexamethylene guanidine phosphate (PHMG-p) is a guanidine-based cationic disinfectant strongly associated with interstitial lung diseases.
Mi Ho Jeong, Yong Joo Park, Ha Ryong Kim
exaly +4 more sources
Epidemiological and toxicological studies indicate that polyhexamethylene guanidine phosphate (PHMG-p) is a guanidine-based cationic disinfectant strongly associated with interstitial lung diseases.
Mi Ho Jeong, Yong Joo Park, Ha Ryong Kim
exaly +4 more sources
Toxicology Letters, 2015 Polyhexamethylene guanidine (PHMG) phosphate is a competitive disinfectant with strong antibacterial activity. However, epidemiologists revealed that inhaled PHMG-phosphate may increase the risk of pulmonary fibrosis associated with inflammation, resulting in the deaths of many people, including infants and pregnant women.
Ha Ryong Kim, Kyu Hyuck Chung
exaly +4 more sources
Inhalation Toxicology, 2019
s Objective: The major active ingredient of humidifier disinfectant, polyhexamethylene guanidine-phosphate (PHMG-P), caused hundreds of deaths with pulmonary fibrosis.
Yong Joo Park, Mi Ho Jeong, Ha Ryong Kim
exaly +4 more sources
s Objective: The major active ingredient of humidifier disinfectant, polyhexamethylene guanidine-phosphate (PHMG-P), caused hundreds of deaths with pulmonary fibrosis.
Yong Joo Park, Mi Ho Jeong, Ha Ryong Kim
exaly +4 more sources
Toxicology Letters, 2018 Polyhexamethylene guanidine phosphate (PHMG-phosphate), an active component of humidifier disinfectant, is suspected to be a major cause of pulmonary fibrosis. Fibrosis, induced by recurrent epithelial damage, is significantly affected by epigenetic regulation, including microRNAs (miRNAs).
D. Shin +4 more
semanticscholar +4 more sources
Respiratory Toxicity of Polyhexamethylene Guanidine Phosphate Exposure in Zebrafish
Zebrafish, 2018 Abstract Humidifier disinfectants containing polyhexamethylene guanidine phosphate (PHMG-P) can induce pulmonary toxicity and has caused human casualties in South Korea since 2006. Thereby, the safety evaluation of household chemicals such as PHMG-P has garnered increased importance.
Hanseul, Oh +9 more
openaire +3 more sources
Comparative toxicity of polyhexamethylene guanidine phosphate in three strains of rats
Molecular & Cellular Toxicology, 2021Although polyhexamethylene guanidine phosphate (PHMG) is the main antibacterial ingredient in humidifier disinfectants, inhalation of PHMG causes severe respiratory diseases, including pulmonary fibrosis and asthma. Many studies using animal models have been conducted to investigate the molecular mechanisms of PHMG-induced pulmonary diseases.
Jong Woo +5 more
semanticscholar +3 more sources
Effects of polyhexamethylene guanidine phosphate on human gingival fibroblasts
Acta Odontologica Scandinavica, 2017 Polyhexamethylene guanidine phosphate (PHMG-P) was compared to chlorhexidine (CHX) in order to determine potential cytotoxic and immune-modulatory effects on human gingival fibroblasts.Cytotoxic effects of PHMG-P and CHX on human gingival fibroblasts were assessed using cell viability assay at various time points and concentrations. The effects of PHMG-
Anton, Vitt +7 more
openaire +3 more sources
Journal of Hazardous Materials, 2020
Biocides are widely used for their effective antiseptic and disinfectant properties, including polyhexamethylene guanidine phosphate (PHMG-P), which is also used as a biocide as it selectively disrupts bacterial cell membrane.
Jinsoo Lee +11 more
semanticscholar +3 more sources
Biocides are widely used for their effective antiseptic and disinfectant properties, including polyhexamethylene guanidine phosphate (PHMG-P), which is also used as a biocide as it selectively disrupts bacterial cell membrane.
Jinsoo Lee +11 more
semanticscholar +3 more sources