Results 131 to 140 of about 379,094 (142)
Some of the next articles are maybe not open access.

Polyhexamethylene guanidine phosphate-induced upregulation of MUC5AC via activation of the TLR-p38 MAPK and JNK axis

Chemico-Biological Interactions, 2019
Epidemiological and toxicological studies indicate that polyhexamethylene guanidine phosphate (PHMG-p) is a guanidine-based cationic disinfectant strongly associated with interstitial lung diseases.
Yong Joo Park   +2 more
exaly   +2 more sources

Prediction of the skin sensitization potential of polyhexamethylene guanidine phosphate, oligo(2-(2-ethoxy)ethoxyethyl) guanidinium chloride, triclosan, and mixtures of these compounds with the excipient propylene glycol through the local lymph node assay: BrdU-FCM

Toxicology and Industrial Health, 2019
The guanidine family of antimicrobial agents, which includes polyhexamethylene guanidine phosphate (PHMG) and oligo(2-(2-ethoxy)ethoxyethyl) guanidinium chloride (PGH), and chlorophenol biocidal chemicals such as 2,4,4′-trichloro-2′-hydroxydiphenyl ether
Yeon-Mi Lim, HyoungAh Kim, Yong Heo
exaly   +2 more sources

Reproductive and developmental toxicity screening of polyhexamethylene guanidine phosphate by oral gavage in rats

Regulatory Toxicology and Pharmacology, 2019
Polyhexamethylene guanidine phosphate (PHMG-P) has effective antimicrobial activity against various microorganisms and has been widely used as a biocide in commercial products.
Sang-Yoon Nam   +2 more
exaly   +2 more sources

Guanidine-based disinfectants, polyhexamethylene guanidine-phosphate (PHMG-P), polyhexamethylene biguanide (PHMB), and oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride (PGH) induced epithelial-mesenchymal transition in A549 alveolar epithelial cells

Inhalation Toxicology, 2019
s Objective: The major active ingredient of humidifier disinfectant, polyhexamethylene guanidine-phosphate (PHMG-P), caused hundreds of deaths with pulmonary fibrosis.
Yong Joo Park   +2 more
exaly   +2 more sources

Time-course transcriptomic alterations reflect the pathophysiology of polyhexamethylene guanidine phosphate-induced lung injury in rats

Inhalation Toxicology, 2019
Objective: Humidifier-disinfectant-induced lung injury is a new syndrome associated with a high mortality rate and characterized by severe hypersensitivity pneumonitis, acute interstitial pneumonia, or acute respiratory distress syndrome ...
Mi-Kyung Song
exaly   +2 more sources

Polyhexamethylene guanidine phosphate induces pyroptosis via reactive oxygen species-regulated mitochondrial dysfunction in bronchial epithelial cells.

Toxicology
Pyroptosis is a form of programmed cell death characterized by gasdermin (GSDM)-mediated pore formation in the cell membrane, resulting in the release of pro-inflammatory cytokines and cellular lysis.
Jun Young Park   +5 more
semanticscholar   +1 more source

A humidifier disinfectant biocide, polyhexamethylene guanidine phosphate, inhalation exposure during pregnancy induced toxicities in rats.

Journal of Hazardous Materials, 2020
Biocides are widely used for their effective antiseptic and disinfectant properties, including polyhexamethylene guanidine phosphate (PHMG-P), which is also used as a biocide as it selectively disrupts bacterial cell membrane.
Jinsoo Lee   +11 more
semanticscholar   +1 more source

Akt and Notch pathways mediate polyhexamethylene guanidine phosphate-induced epithelial-mesenchymal transition via ZEB2.

Toxicology and Applied Pharmacology, 2019
Polyhexamethylene guanidine phosphate (PHMG-p), an antimicrobial additive, was used as a humidifier disinfectant in Korea and caused severe lung injuries, including lung fibrosis, in hundreds of victims.
M. Jeong   +3 more
semanticscholar   +1 more source

Comparative toxicity of polyhexamethylene guanidine phosphate in three strains of rats

Molecular & Cellular Toxicology, 2021
Jong Woo   +5 more
semanticscholar   +2 more sources

Evaluating the comparative MT1B, MT1F, MT1G, and MT1H expression in human pulmonary alveolar epithelial cells treated with polyhexamethylene guanidine-phosphate, chloromethylisothiazolinone/methylisothiazolinone, oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride, benzalkonium chloride, and sodium d

Molecular & Cellular Toxicology, 2022
Jaeyoung Kim   +13 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy