Results 1 to 10 of about 34,466 (298)

Polymeric-Micelle-Based Delivery Systems for Nucleic Acids [PDF]

open access: yesPharmaceutics, 2023
Nucleic acids can modulate gene expression specifically. They are increasingly being utilized and show huge potential for the prevention or treatment of various diseases.
Genada Sinani   +3 more
doaj   +2 more sources

Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle [PDF]

open access: yesPharmaceutics, 2018
Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water ...
Gyubin Noh   +8 more
doaj   +2 more sources

Polymeric Micelle of A3B-Type Lactosome as a Vehicle for Targeting Meningeal Dissemination [PDF]

open access: yesNanomaterials, 2018
Polymeric micelle of the A3B-type lactosome comprising (poly(sarcosine))3-b-poly(l-lactic acid) was labeled with 111In. The 111In-labeled A3B-type lactosome was administered to the model mice bearing meningeal dissemination and bone metastasis at ...
Kensuke Kurihara   +5 more
doaj   +2 more sources

Synthesis and evaluation of polymeric micelle containing piperacillin/tazobactam for enhanced antibacterial activity [PDF]

open access: yesDrug Delivery, 2019
Infections caused by multidrug-resistant bacteria such as P. aeruginosa are important therapeutic complications. Piperacillin/Tazobactam is considered a safe antimicrobial agent.
Milani Morteza   +4 more
doaj   +2 more sources

Comparative Stability of Synthetic and Natural Polymeric Micelles in Physiological Environments: Implications for Drug Delivery [PDF]

open access: yesPharmaceutics
Polymeric micelles are widely studied as nanocarriers for hydrophobic drugs, yet their structural stability under physiological conditions remains a major limitation.
Hurriyet Polat   +4 more
doaj   +2 more sources

Sodium cholate-enhanced polymeric micelle system for tumor-targeting delivery of paclitaxel [PDF]

open access: yesInternational Journal of Nanomedicine, 2017
Xiaomin Zhang,1,2 Yibo Wu,1 Min Zhang,1 Jing Mao,3 Yun Wu,4 Yingxin Zhang,2 Ju Yao,2 Chang Xu,2 Wenli Guo,1 Bo Yu2 1Beijing Key Laboratory of Special Elastomeric Composite Materials, Beijing Institute of Petrochemical Technology, Beijing, 2Push-Kang ...
Zhang X   +9 more
doaj   +2 more sources

Development of a reverse-phase HPLC method for the simultaneous determination of curcumin and dexamethasone in polymeric micelles [PDF]

open access: yesFuture Science OA
Background A rapid, simple, accurate, and robust reverse-phase high-performance liquid chromatography (RP-HPLC) method was developed to quantify curcumin and dexamethasone in polymeric micelle nanoparticle formulations simultaneously.Methods The ...
Dana Haj-Ali   +3 more
doaj   +2 more sources

Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2022
In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging.
Nicole Lecot   +7 more
doaj   +1 more source

Polymeric Micelles in Cancer Immunotherapy [PDF]

open access: yesMolecules, 2021
Cancer immunotherapies have generated some miracles in the clinic by orchestrating our immune system to combat cancer cells. However, the safety and efficacy concerns of the systemic delivery of these immunostimulatory agents has limited their application.
Zhuoya Wan   +7 more
openaire   +3 more sources

Enhanced thermodynamic, pharmacokinetic and theranostic properties of polymeric micelles via hydrophobic core-clustering of superparamagnetic iron oxide nanoparticles

open access: yesBiomaterials Research, 2022
Background Superparamagnetic iron oxide nanoparticles (SPIO) have been applied for decades to design theranostic polymeric micelles for targeted cancer therapy and diagnostic MR imaging. However, the effects of SPIO on the physicochemical, and biological
Yixin Jiang   +5 more
doaj   +1 more source

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