Results 21 to 30 of about 34,466 (298)
pH-responsive polymeric micelles self-assembled from amphiphilic copolymer modified with lipid used as doxorubicin delivery carriers [PDF]
Royal Society Open Science, 2018 In the present study, a novel pH-responsive amphiphilic copolymer, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)] conjugated poly(β-amino esters) (DSPE-b-PEG-b-PAE-b-PEG-b-DSPE), was designed and successfully synthesized
Xin Xin Zhou +3 more
doaj +1 more source
Intelligent delivery of antitumor drugs mediated by polymeric nanomicelles: a review [PDF]
Química Nova, 2023 Cancer therapy represents a challenge, even with the current scientific developments. Over the years, several studies have shown that the application of antitumor drug nanocarriers is an efficient strategy; however, it requires further improvement ...
Raquel dos Santos Martins +2 more
doaj +1 more source
Self-assembly of multi-component fluorescent molecular logic gates in micelles [PDF]
, 2016 A recent strategy for developing supramolecular logic gates in water is based on combinations of molecules via self-assembly with surfactants, which eliminates the need for time-consuming synthesis. The self-assembly of surfactants and lumophores and
Costa, Paola F. da +2 more
core +1 more source
Highlights on polymeric micelles as versatile nanocarriers for drug transporting
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Polymeric micelles are nanoscale core-shell structures formed by amphiphilic (block or graft) copolymers, that can self-aggregate in an aqueous medium.
Hussein A. Abdul Hussein +1 more
doaj +1 more source
Polymeric micelles–mediated photodynamic therapy
, 2023 Polymeric micelles (PM) have been demonstrating high potential as multifunctional therapeutic nanoplatforms for anticancer photodynamic therapy (PDT). PM increase photosensitizer (PS) accumulation in tumor tissues, thus improving its antitumor effect. The development of PM responsive to endogenous (e.g., pH, reducing agents, and hypoxia) or exogenous ...
de Santana, Willian Max O.S. +4 more
openaire +2 more sources
Toxicity and immunogenicity concerns related to PEGylated-micelle carrier systems: a review
Science and Technology of Advanced Materials, 2019 Polymeric-micelle carrier systems have emerged as a novel drug-carrier system and have been actively studied for anticancer drug targeting. In contrast, toxicological and immunological concerns related to not only polymeric-micelle carrier systems, but ...
Kouichi Shiraishi, Masayuki Yokoyama
doaj +1 more source
Molecules, 2023 The current research is aimed at investigating the relationship between the formulation components and conditions in the case of a binary drug delivery system, where antidiabetic drugs are co-formulated into polymeric micelles embedded in sodium alginate.
Bence Sipos +3 more
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Hydrophobically modified polyelectrolytes as potential drugs reservoirs of n-alkyl-nitroimidazoles [PDF]
, 2007 Indexación: ScieloThe solubilization of three commercial drugs (ornindazole, metronidazole and tinidazole) and model compounds (N-alkyl-2-methyl-4-nitroimidazoles) on aggregates formed by anionic polyelectrolytes, carrying alkyl side chains of different ...
Acevedo, Betsabé +3 more
core +1 more source
Molecules, 2018 The low oral bioavailability of ciprofloxacin is associated with two distinct challenges: its low aqueous solubility and efflux by p-glycoproteins (P-gp) in the intestinal membrane.
Behzad Sharif Makhmal Zadeh +2 more
doaj +1 more source
Corrosion Inhibition of Low-Carbon Steel by Hydrophobic Organosilicon Dispersions
Metals, 2021 This article proposes a method for obtaining stable hydrophobic inhibitor dispersions, where the micelle core contains a hydrophobic solvent, a corrosion inhibitor and an organosilane.
Yuri Makarychev +3 more
doaj +1 more source