Results 11 to 20 of about 59,311 (300)

Validation of smart nanoparticles as controlled drug delivery systems: loading and pH-dependent release of pilocarpine [PDF]

open access: yes, 2017
Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action. The present work assesses loading kinetics of
Galbis Fuster, Elsa   +4 more
core   +6 more sources

Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy

open access: yesNanoscale Research Letters, 2020
Oleanolic acid has been used only as a subsidiary agent in cosmetic products. The aim of the study is to show the effect of oleanolic acid as an active ingredient for the alleviation of wrinkles in humans and to develop a polymeric micelle formulation ...
Joo Young An   +6 more
doaj   +1 more source

Characterizing the Drug-Release Enhancement Effect of Surfactants on Megestrol-Acetate-Loaded Granules

open access: yesPharmaceuticals, 2022
In this study, the effect of Cremophor® RH 40 (CR 40) classic micelles and Soluplus® (SP) polymeric micelles were investigated on a novel granule-type drug-delivery system containing megestrolacetate (MGA).
Gábor Katona   +4 more
doaj   +1 more source

Exploring the Application of Micellar Drug Delivery Systems in Cancer Nanomedicine

open access: yesPharmaceuticals, 2023
Various formulations of polymeric micelles, tiny spherical structures made of polymeric materials, are currently being investigated in preclinical and clinical settings for their potential as nanomedicines.
Qi Wang   +3 more
doaj   +1 more source

Catalytic polymeric nanoreactors : more than a solid supported catalyst [PDF]

open access: yes, 2012
Polymeric nanostructures can be synthesized where the catalytic motif is covalently attached within the core domain and protected from the environment by a polymeric shell.
Bosman, Liu, Wang, Yan
core   +2 more sources

Development of fluorescent- and radio-traceable T1307-polymeric micelles as biomedical agents for cancer diagnosis: biodistribution on 4T1 tumor-bearing mice [PDF]

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2022
In recent years, nanocarriers have been studied as promising pharmaceutical tools for controlled drug-delivery, treatment-efficacy follow-up and disease imaging.
Nicole Lecot   +7 more
doaj   +1 more source

Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery

open access: yesNanomaterials, 2021
Four-arm star-shaped (denoted as ‘S’) polymer adamantane-[poly(lactic-co-glycolic acid)-b-poly(N,N’-diethylaminoethyl methacrylate) poly(ethylene glycol) monomethyl ether]4 (S-PLGA-D-P) and its linear (denoted as ‘L’) counterpart (L-PLGA-D-P) were ...
Weiqiu Wen, Chong Guo, Jianwei Guo
doaj   +1 more source

Chitosan-g-oligo(epsilon-caprolactone) polymeric micelles: microwave-assisted synthesis and physicochemical and cytocompatibility characterization [PDF]

open access: yes, 2015
With the aim to produce mucoadhesive polymeric micelles for drug administration by mucosal routes, chitosan-g-oligo(epsilon-caprolactone) copolymers were synthesized by the microwave-assisted ring-opening polymerization of epsilon-caprolactone using ...
Calderon, Marcelo   +5 more
core   +1 more source

Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region

open access: yesPharmaceutics, 2021
Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula   +8 more
doaj   +1 more source

Poly(2-oxazolines) in biological and biomedical application contexts. [PDF]

open access: yes, 2007
Polyoxazolines of various architectures and chemical functionalities can be prepared in a living and therefore controlled manner via cationic ring-opening polymerisation.
Adams, Nico, Schubert, Ulrich S
core   +1 more source

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