Results 41 to 50 of about 4,829 (203)
Bioengineering & Translational Medicine, 2023 Membrane proteins (MPs) play key roles in cellular signaling pathways and are responsible for intercellular and intracellular interactions. Dysfunctional MPs are directly related to the pathogenesis of various diseases, and they have been exploited as ...
Chih Hung Lo, Jialiu Zeng
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Cascade Reactions in Multicompartmentalized Polymersomes [PDF]
Angewandte Chemie, 2013 AbstractEnzyme‐filled polystyrene‐b‐poly(3‐(isocyano‐L‐alanyl‐aminoethyl)thiophene) (PS‐b‐PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene‐b‐poly(ethylene oxide) (PB‐b‐PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An
Peters, R.J.R.W. +6 more
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Polymerization-Induced Polymersome Fusion [PDF]
Journal of the American Chemical Society, 2019 The dynamic interactions of membranes, particularly their fusion and fission, are critical for the transmission of chemical information between cells. Fusion is primarily driven by membrane tension built up through membrane deformation. For artificial polymersomes, fusion is commonly induced via the external application of a force field. Herein, fusion-
Spyridon Varlas +5 more
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Macrophage Targeting pH Responsive Polymersomes for Glucocorticoid Therapy
Pharmaceutics, 2019 Glucocorticoid (GC) drugs are the cornerstone therapy used in the treatment of inflammatory diseases. Here, we report pH responsive poly(2-methacryloyloxyethyl phosphorylcholine)−poly(2-(diisopropylamino)ethyl methacrylate) (PMPC−PDPA ...
Virgínia M. Gouveia +7 more
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Pharmaceutics, 2023 The development of new approaches for the treatment of the increasingly antibiotic-resistant pathogen Pseudomonas aeruginosa was targeted by enhancing the effect of local antimicrobial photodynamic therapy (aPDT) using poly(ethylene glycol)-block-poly ...
Kawaljit Kaur +3 more
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Electromechanical Limits of Polymersomes [PDF]
Physical Review Letters, 2001 Physical Review ...
Aranda-Espinoza, Helim +3 more
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Advanced Science, 2019 Understanding the diffusion of nanoparticles through permeable membranes in cell mimics paves the way for the construction of more sophisticated synthetic protocells with control over the exchange of nanoparticles or biomacromolecules between different ...
Hannes Gumz +7 more
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Design of chimaeric polymersomes
Faraday Discussions, 2005 We discuss the development of hierarchical polymer particles, or variegated polymersome composites, in which at least two different components are phase separated within one polymersome chimaera. We briefly discuss the present status in experimental polymersome research, and then discuss a speculative design strategy, based on mesoscopic simulations ...
J. G. E. M. Fraaije +4 more
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Molecules, 2022 Limited tissue selectivity and targeting of anticancer therapeutics in systemic administration can produce harmful side effects in the body. Various polymer nano-vehicles have been developed to encapsulate therapeutics and prevent premature drug release.
Veronika Kozlovskaya +6 more
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International Journal of Pharmaceutics: X, 2020 The past few decades have seen a significant rise in research into alternative polymer based nanosized unilamellar drug delivery systems, termed polymersomes.
Noorjahan Aibani +2 more
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