Results 51 to 60 of about 303,582 (318)

Microsatellite Loci Reveal Heterozygosis and Population Structure in the Critically Endangered Southern River Terrapin (Batagur affinis ssp.) of Peninsular Malaysia

open access: yesChemistry Proceedings, 2022
These freshwater turtles are found across Indochina, mostly in large rivers. There is a lack of genetic research concentrating on Malaysia’s southern river terrapin (Batagur affinis) population.
Mohd Hairul Mohd Salleh, Yuzine Esa
doaj   +1 more source

Genetic variability of cultivated cowpea in Benin assessed by random amplified polymorphic DNA [PDF]

open access: yes, 2008
Characterization of genetic diversity among cultivated cowpea [Vigna unguiculata (L.) Walp.] varieties is important to optimize the use of available genetic resources by farmers, local communities, researchers and breeders.
Zannou, A.   +6 more
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes [PDF]

open access: yes, 2010
peer-reviewedBackground: About forty human diseases are caused by repeat instability mutations. A distinct subset of these diseases is the result of extreme expansions of polymorphic trinucleotide repeats; typically CAG repeats encoding poly-glutamine ...
Herman Raadsma   +30 more
core   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Salvianolic Acid A Activates Nrf2-Related Signaling Pathways to Inhibit Ferroptosis to Improve Ischemic Stroke

open access: yesMolecules
Ischemic stroke is a serious disease that frequently occurs in the elderly and is characterized by a complex pathophysiology and a limited number of effective therapeutic agents. Salvianolic acid A (SAL-A) is a natural product derived from the rhizome of
Yu-Fu Shang   +7 more
doaj   +1 more source

Polymorphism and apartness.

open access: yesNotre Dame Journal of Formal Logic, 1991
The author gives a new intuitionistic model \({\mathcal C}\) for the second- order polymorphic lambda calculus. \({\mathcal C}\) is a proper subcategory of the category \({\mathcal M}\) of realizability-valued modest sets on which earlier intuitionistic models have been constructed.
openaire   +4 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

ANALYSIS ON Alu-I GROWTH HORMONE (GHAlu-I) GENE IN BALI CATTLE [PDF]

open access: yesJournal of the Indonesian Tropical Animal Agriculture, 2011
The research was conducted to identify Alu-I locus of growth hormone (GH) gene in Bali cattle by using 232 blood samples collected from Bali and Lombok islands.
Jakaria, R. R. Noor
doaj  

Isolation and characterization of 28 polymorphic microsatellite loci in black carp (Mylopharyngodon piceus) [PDF]

open access: yes, 2013
This study reports the isolation and characterization of 28 polymorphic microsatellite loci developed from black carp (Mylopharyngodon piceus), which is an important freshwater fish in China. The polymorphism was assessed with 32 individuals.
Cao, Wenxuan   +3 more
core   +1 more source

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