Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Association of two issr markers with the growth traits of saburai does (capra hircus) [PDF]
Kafkas Universitesi Veteriner Fakültesi DergisiSaburai goat (Capra hircus) developed by the farmers at Tanggamus Regency, Indonesia and originated from the crossbreeding between Boer buck and Ettawa grade doe for meat production purpose.
Alfian DESTOMO +10 more
doaj +1 more source
Using Synthetic Domain Theory to Prove Operational Properties of a Polymorphic Programming Language Based on Strictness [PDF]
, 2004 We present a simple and workable axiomatization of domain theory within intuitionistic set theory, in which predomains are (special) sets, and domains are algebras for a simple equational theory.
Rosolini, Giuseppe, Simpson, Alex
core
Investigating the melting behaviour of polymorphic zeolitic imidazolate frameworks [PDF]
, 2020 Recently, there has been growing interest in the amorphous states of metal–organic frameworks (MOFs). Particular focus has been given to melt-quenched MOF glasses. In this work, to improve our understanding of the factors influencing melting, the thermal
Bennett TD +17 more
core +2 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Sustained polymorphic ventricular tachycardia in a calf [PDF]
Eurasian Journal of Veterinary SciencesSustained polymorphic ventricular tachycardia is a type of ventricular dysrhythmias which originated from more than one focus in ventricle and may lead to fatal arrhythmias like as ventricular fibrillation and sudden death.
Amir Naseri, Merve Ider, Mahmut Ok
doaj
Studies on polymorphic alu insertions and genomic diversity within the major histocompatibility complex [PDF]
, 2005 After the initiation of the human genome sequencing project and the introduction of the field of 'bioinformatics', interest in human genetic diversity studies has been increased.
Dunn, David Suliman
core
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Revista Brasileira de Fruticultura, 2010 O cultivo comercial do maracujá é afetado por diversos problemas fitossanitários, os quais contribuem para quebras de produção e significativa redução da vida útil dos plantios. Em algumas situações, a incidência de doenças pode inviabilizar o cultivo do
Mariana da Silva Paula +3 more
doaj
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source