Results 61 to 70 of about 625,935 (339)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Programmable data processing method and system design for polymorphic network
Tongxin xuebao, 2022 Aiming at the problems of compatible with multiple route identification, network protocols and network application data processing faced by multimodal networks, a programmable data processing method compatible with multiple modes was proposed.Through the
Jinlin WANG +3 more
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Chemistry Proceedings, 2022 These freshwater turtles are found across Indochina, mostly in large rivers. There is a lack of genetic research concentrating on Malaysia’s southern river terrapin (Batagur affinis) population.
Mohd Hairul Mohd Salleh, Yuzine Esa
doaj +1 more source
Polymorphic Endpoint Types for Copyless Message Passing
, 2011 We present PolySing#, a calculus that models process interaction based on copyless message passing, in the style of Singularity OS. We equip the calculus with a type system that accommodates polymorphic endpoint types, which are a variant of polymorphic ...
Bono, Viviana, Padovani, Luca
core +2 more sources
Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia [PDF]
, 2015 Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a difficult-to-diagnose cause of sudden cardiac death (SCD). We identified a family of 1400 individuals with multiple cases of CPVT, including 36 SCDs during youth.
Allegue, Catarina +12 more
core +3 more sources
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
ANALYSIS ON Alu-I GROWTH HORMONE (GHAlu-I) GENE IN BALI CATTLE [PDF]
Journal of the Indonesian Tropical Animal Agriculture, 2011 The research was conducted to identify Alu-I locus of growth hormone (GH) gene in Bali cattle by using 232 blood samples collected from Bali and Lombok islands.
Jakaria, R. R. Noor
doaj
Why Just Boogie? Translating Between Intermediate Verification Languages
, 2016 The verification systems Boogie and Why3 use their respective intermediate languages to generate verification conditions from high-level programs. Since the two systems support different back-end provers (such as Z3 and Alt-Ergo) and are used to encode ...
Ameri, Michael, Furia, Carlo A.
core +1 more source