Results 111 to 120 of about 224,359 (239)

Genetic variants of SLC6A4 and risk of coronary artery disease: insights from North Indian population. [PDF]

open access: yesOrphanet J Rare Dis
Raina JK   +6 more
europepmc   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

open access: yesSmall, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun   +12 more
wiley   +1 more source

Functional and Structural Analyses of Diverse G‐Quadruplex and Non‐G‐Quadruplex Structures Formed by Guanine‐Rich Nucleic Acids: A Study on the Insulin Aptamer

open access: yesSmall, EarlyView.
IGA3, a guanine‐rich insulin aptamer, adopts different structures depending on environmental conditions. Under low cation concentrations, IGA3 forms a non‐G‐quadruplex structure that interacts with insulin. This finding highlights that guanine‐rich nucleic acids, in structures other than G‐quadruplex, can also bind to proteins, revealing valuable ...
Naoya Iwano   +9 more
wiley   +1 more source

Chalcogenide Materials in Water Purification: Advances in Adsorptive and Photocatalytic Removal of Organic Pollutants

open access: yesSmall, EarlyView.
Chalcogenide materials emerge as efficient agents for water purification, enabling adsorptive and photocatalytic removal of dyes, pharmaceuticals, and pesticides. This review highlights recent advances in synthesis, structural tuning, and pollutant interaction mechanisms, while addressing challenges of toxicity and scalability. Insights into the future
Damilola Caleb Akintayo   +2 more
wiley   +1 more source

Forging a New Frontier: Antimicrobial Peptides and Nanotechnology Converging to Conquer Gastrointestinal Pathogens

open access: yesSmall, EarlyView.
This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales   +10 more
wiley   +1 more source

Genetic Polymorphism of <i>CYP2R1</i>, <i>CYP27A1</i>, <i>CYP27B1</i>, and Vitamin D Metabolites Plasma Levels in Patients with Cardiovascular Disease: A Pilot Study. [PDF]

open access: yesBiomolecules
Abouzid M   +8 more
europepmc   +1 more source

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