Results 181 to 190 of about 6,098 (217)

[11] Mutational detection by single-strand conformational polymorphism

1995
Summary In addition to providing valuable information on the possible location of mutations within particular genes, PCR-SSCP is a powerful method for converting random DNA fragments to polymorphic markers for linkage analysis. In addition, once a given mutation is identified, a specific oligonucleotide primer can be designed such that the 3′ most ...
Nabeel Bardeesy, Jerry Pelletier
openaire   +1 more source

Single-Strand Conformational Polymorphism Analysis: Basic Principles and Routine Practice

2005
Single-strand conformational polymorphism (SSCP) analysis is a simple and sensitive technique for mutation detection and genotyping. The principle of SSCP analysis is based on the fact that single-stranded DNA has a defined conformation. Altered conformation due to a single base change in the sequence can cause single-stranded DNA to migrate ...
Yanbin, Dong, Haidong, Zhu
openaire   +2 more sources

High-throughput single-strand conformation polymorphism analysis by capillary electrophoresis

Journal of Chromatography B: Biomedical Sciences and Applications, 2000
Mutation detection plays a great role in genetic and medical research and clinical diagnosis of inherited diseases and particular cancers. Single-strand conformation polymorphism (SSCP) analysis is one of the most popular methods for detection of mutations.
openaire   +2 more sources

Single-Strand Conformation Polymorphism Analysis

Cold Spring Harbor Protocols, 2006
Anne E, Jedlicka, Steven R, Kleeberger
openaire   +2 more sources

Single-Strand Conformation Polymorphism Mutation Analysis of the p53 Gene

2003
Single-strand conformation polymorphism (SSCP) is a rapid and convenient procedure by which differences in the base composition of short DNA strands may be detected (1, 2). A useful application of this is in the comparison of polymerase chain reaction (PCR) generated products from gene coding sequences of unknown or patient material with a known wild ...
openaire   +2 more sources

SSCP (single strand conformation polymorphism)

EMC - Biologie médicale, 2008
openaire   +1 more source

Single-Strand Conformation Polymorphism (SSCP) Analysis

1998
William C. Jordan, Katherine Foley, Michael W. Bruford   +2 more
openaire   +1 more source

Breaking and joining single-stranded DNA: the HUH endonuclease superfamily

Nature Reviews Microbiology, 2013
Michael Chandler, Fernando De La Cruz, Fred Dyda   +2 more
exaly  

Single Strand Conformation Polymorphism (SSCP) Analysis

2008
Kim Hung Leung, Shea Ping Yip
openaire   +1 more source

REPLICATION PROTEIN A:A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism

Annual Review of Biochemistry, 1997
Marc S Wold
exaly