Results 21 to 30 of about 20,043 (225)

Identification of Five Putative Yeast RNA Helicase Genes [PDF]

, 1990
The RNA helicase gene family encodes a group of eight homologous proteins that share regions of sequence similarity. This group of evolutionarily conserved proteins presumably all utilize ATP (or some other nucleoside triphosphate) as an energy source ...
Abelson, John, Arenas, Jaime, Chang, Tien-Hsien   +2 more
core   +1 more source

rpoB Gene Mutations in Rifampin-Resistant Mycobacterium tuberculosis Identified by Polymerase Chain Reaction Single-Stranded Conformational Polymorphism

Emerging Infectious Diseases, 2001
The use of polymerase chain reaction-single-stranded conformational polymorphism (PCR-SSCP) to study rpoB gene mutations in rifampin-resistant (RIFr) Mycobacterium tuberculosis has yielded contradictory results.
Miriam Bobadilla-del-Valle, Alfredo Ponce-de-Leon, Catalina Arenas-Huertero, Gilberto Vargas-Alarcon, Midori Kato-Maeda, Peter M. Small, Patricia Couary, Guillermo M. Ruiz-Palacios, Jose Sifuentes-Osornio   +8 more
doaj   +1 more source

Formation of a Unique Cluster of G-Quadruplex Structures in the HIV-1 nef Coding Region: Implications for Antiviral Activity [PDF]

, 2013
G-quadruplexes are tetraplex structures of nucleic acids that can form in G-rich sequences. Their presence and functional role have been established in telomeres, oncogene promoters and coding regions of the human chromosome.
Frasson, Ilaria, Nadai, Matteo, Palumbo, Manlio, Palù, Giorgio, Perrone, Rosalba, Poe, Jerrod A., Qiu, Jianming, Richter, Sara N., Smithgall, Thomas E.   +8 more
core   +2 more sources

DNA Renaturation at the Water-Phenol Interface [PDF]

, 2003
We study DNA adsorption and renaturation in a water-phenol two-phase system, with or without shaking. In very dilute solutions, single-stranded DNA is adsorbed at the interface in a salt-dependent manner.
121, 125, 23, 262, 27, 276, 28, 289, 35, 376, 38, 381, 395, 41, 52, 56, 7, 740, 77, 82, 90, 90, 98, 98, Alberts, Anderson, Anderson, Belhachemi, Berg, Berg, Bernal, Brahms, Braun, Campell, Carri, Carrington, Cech, Chan, Chaperon, Chomczynski, Chow, Christiansen, Craig, Davis, Deamer, DiMarzio, Duckett, Eigen, Eigen, Eisenberg, Escara, Felsenfeld, Fleming, Gennes, Gierer, Gilbert, Gold, Grassmann, Grosberg, Hagenmuller, Hammes, Hearst, Hegner, Helmer, Herschlag, Herskovits, Hill, Jaeger, Joanicot, Joyce, Joyce, Joyce, Katcher, Kauzmann, Kirby, Kirby, Kirby, Kohne, Kowalczykowski, Lahav, Lang, Laurent, Lennard-Jones, Leo, Lerman, Levine, Lohman, Ma, Maier, Maier, Mandell, Manning, Marmur, Marmur, Massie, Meijering, Meuthen, Miller, Morimatsu, Nadassi, Nandi, Neidle, Noller, Oparin, Pace, Pace, Paecht-Horowitz, Papafil, Pelta, Perutz, Piechowska, Piechowska, Pontius, Prigogine, Pusztai, Pörschke, Rhodes, Richter, Riggs, Robertson, Rothman, Saenger, Saito, Saxinger, Schaper, Schürmann, Sevag, Sikorav, Singer, Sinsheimer, Skinner, Smith, Smoluchowski, Studier, Studier, Szostak, Tabor, Tikhonenko, Timmermans, Tor, Tsang, Tsuchihashi, Ts’o, Ts’o, Vesnaver, Wagner, Wang, Ward, Weinstock, Westhof, Wetmur, Wetmur, Widom, Wieder, Winter, Woese, Wolfe, Zaks, Zaks, Zasloff, Zhulina, Ölçer   +161 more
core   +4 more sources

Mutation analysis of genes that control the G1/S cell cycle in melanoma: TP53, CDKN1A, CDKN2A, and CDKN2B

BMC Cancer, 2005
Background The role of genes involved in the control of progression from the G1 to the S phase of the cell cycle in melanoma tumors in not fully known.
López-Nevot Miguel, Serrano Salvio, Cabrera Carmen M, Soto José   +3 more
doaj   +1 more source

Variability of a portion of RNA 3 containing the coat protein gene of Citrus variegation virus (CVV) using single-strand conformation polymorphism (SSCP) [PDF]

, 2002
A portion of RNA 3 of Citrus variegation virus (CVV), comprising part of the intergenic region and the coat protein (CP) gene from eight viral isolates, was amplified by RT-PCR and cloned.
Azeddoug, H., Bennani, B., Nolasco, Gustavo, Zemzami, M.   +3 more
core   +3 more sources

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Nonradioactive Characterization of Low-Level Heteroplasmic Mitochondrial DNA Mutations by SSCP-PCR Enrichment

BioTechniques, 1996
Mitochondrial DNA (mtDNA) mutations have been implicated in an increasing number of human diseases. Many of these mutations are heteroplasmic and are only present at low levels in readily accessible human tissue such as blood.
Emma J. Sherratt, Andrew W. Thomas, James W. Gagg, John C. Alcolado   +3 more
doaj   +1 more source

Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology. [PDF]

, 2013
Deregulation of mini-chromosome maintenance (MCM) proteins is associated with genomic instability and cancer. MCM complexes are recruited to replication origins for genome duplication.
Brewster, Aaron, Chen, Xiaojiang S, Forsburg, Susan L, Fu, Yang, Ranatunga, Nimna, Slaymaker, Ian M, Toso, Daniel B, Zhou, Z Hong   +7 more
core   +1 more source

Optimization of Nonisotopic PCR–Single-Strand Conformation Polymorphism Analysis [PDF]

Clinical Chemistry, 1997
PCR–single-strand conformation polymorphism (SSCP) analysis is an attractive technique used to screen for unknown mutations because of its simplicity and widespread applicability (1). The technique relies on single-nucleotide variations modifying the conformation of single-stranded DNA and therefore its mobility in polyacrylamide gels. The detection of
H, Blanché, C, Valette, C, Bellanné-Chantelot   +2 more
openaire   +2 more sources